RPL11，一种决定羧苄青霉素和庆大霉素抗性的铜绿假单胞菌R因子。
RPL11, an R factor of Pseudomonas aeruginosa determining carbenicillin and gentamicin resistance.
作者信息
Korfhagen T R, Loper J C
出版信息
Antimicrob Agents Chemother. 1975 Jan;7(1):69-73. doi: 10.1128/AAC.7.1.69.
Abstract
R factor RPL11 from Pseudomonas aeruginosa determines multiple drug resistance including resistance to gentamicin and carbenicillin. The host range and incompatibility properties of RPL11 are those of incompatibility group P-2. Strains harboring the factor are not altered with respect to the major immunotypes 1 through 7 of Parke-Davis, or with respect to pyocin type by using the 18 indicators of Jones and co-workers. Analytical ultracentrifugation of crude extracts of R factor-containing strains shows a band of satellite DNA with a buoyant density of 1.717 g/cm(3).
摘要
来自铜绿假单胞菌的R因子RPL11决定了多重耐药性，包括对庆大霉素和羧苄青霉素的耐药性。RPL11的宿主范围和不相容性特性属于不相容性P-2组。携带该因子的菌株在Parke-Davis的主要免疫型1至7方面，或在使用Jones及其同事的18种指示菌的情况下在绿脓菌素类型方面均未发生改变。对含有R因子的菌株粗提物进行分析超速离心，结果显示出一条卫星DNA带，其浮力密度为1.717 g/cm³。
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