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1
RPL11, an R factor of Pseudomonas aeruginosa determining carbenicillin and gentamicin resistance.RPL11，一种决定羧苄青霉素和庆大霉素抗性的铜绿假单胞菌R因子。
Antimicrob Agents Chemother. 1975 Jan;7(1):69-73. doi: 10.1128/AAC.7.1.69.
2
Pseudomonas aeruginosa R factors determining gentamicin plus carbenicillin resistance from patients with urinary tract colonizations.从尿路定植患者中分离出的决定庆大霉素加羧苄青霉素耐药性的铜绿假单胞菌R因子
Antimicrob Agents Chemother. 1975 Jan;7(1):64-8. doi: 10.1128/AAC.7.1.64.
3
Transferable resistance to carbenicillin and gentamicin in Pseudomonas aeruginosa.铜绿假单胞菌对羧苄青霉素和庆大霉素的可转移性耐药性。
S Afr Med J. 1974 Jun 12;48(28):1185-6.
4
Multiresistant plasmids from Pseudomonas aeruginosa highly resistant to either or both gentamicin and carbenicillin.来自铜绿假单胞菌的多重耐药质粒，对庆大霉素和羧苄青霉素中的一种或两种具有高度抗性。
Antimicrob Agents Chemother. 1976 Jun;9(6):866-73. doi: 10.1128/AAC.9.6.866.
5
Synergistic activity of gentamicin plus carbenicillin upon Pseudomonas aeruginosa: its relationship with pyocin and antibiotic susceptibility.庆大霉素联合羧苄西林对铜绿假单胞菌的协同活性：其与绿脓菌素及抗生素敏感性的关系。
Microbios. 1977;18(72):79-86.
6
Pyocin sensitivity of pseudomonas aeruginosa pretreated with antibiotics.用抗生素预处理的铜绿假单胞菌的绿脓菌素敏感性
Can J Microbiol. 1977 May;23(5):583-8. doi: 10.1139/m77-084.
7
Gentamicin-carbenicillin synergy among gentamicin resistant Pseudomonas aeruginosa.庆大霉素耐药的铜绿假单胞菌中庆大霉素与羧苄西林的协同作用
Ann Clin Lab Sci. 1982 Mar-Apr;12(2):116-8.
8
Synergy studies with Pseudomonas aeruginosa resistant to gentamicin and/or carbenicillin.对庆大霉素和/或羧苄青霉素耐药的铜绿假单胞菌的协同研究。
Chemotherapy. 1978;24(5):283-9. doi: 10.1159/000237794.
9
Susceptibility of recent isolates of Pseudomonas aeruginosa to gentamicin, polymyxin, and five penicillins, with observations on the pyocin and immunotypes of the strains.铜绿假单胞菌近期分离株对庆大霉素、多粘菌素和五种青霉素的敏感性，以及对菌株的绿脓菌素和免疫型的观察
Appl Microbiol. 1971 Nov;22(5):870-5. doi: 10.1128/am.22.5.870-875.1971.
10
Transfer of gentamicin resistance from Pseudomonas aeruginosa strains highly resistant to gentamicin and carbenicillin.庆大霉素耐药性从对庆大霉素和羧苄西林高度耐药的铜绿假单胞菌菌株的转移。
Chemotherapy. 1973;18(4):229-34. doi: 10.1159/000221266.

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Novel Chromosome-Borne Accessory Genetic Elements Carrying Multiple Antibiotic Resistance Genes in .新型染色体携带多种抗生素耐药基因的附加遗传元件在 …… 中
Front Cell Infect Microbiol. 2021 Mar 18;11:638087. doi: 10.3389/fcimb.2021.638087. eCollection 2021.
2
Propagation of TEM- and PSE-type beta-lactamases among amoxicillin-resistant Salmonella spp. isolated in France.TEM型和PSE型β-内酰胺酶在法国分离出的耐阿莫西林沙门氏菌中的传播情况。
Antimicrob Agents Chemother. 1999 Oct;43(10):2430-6. doi: 10.1128/AAC.43.10.2430.
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Spread of a "Pseudomonas-specific" beta-lactamase to plasmids of enterobacteria.一种“假单胞菌属特异性”β-内酰胺酶向肠杆菌属质粒的传播。
J Bacteriol. 1982 Feb;149(2):700-7. doi: 10.1128/jb.149.2.700-707.1982.
4
Immunological comparison between OXA-2 beta-lactamase and those mediated by other R plasmids.OXA-2β-内酰胺酶与其他R质粒介导的β-内酰胺酶之间的免疫学比较。
Antimicrob Agents Chemother. 1985 Jun;27(6):989-91. doi: 10.1128/AAC.27.6.989.
5
Nosocomial infection with gentamicin-carbenicillin-resistant Pseudomonas aeruginosa.由耐庆大霉素-羧苄西林的铜绿假单胞菌引起的医院感染。
Antimicrob Agents Chemother. 1976 Oct;10(4):626-9. doi: 10.1128/AAC.10.4.626.
6
Recombination between plasmids of incompatibility groups P-1 and P-2.不相容群P-1和P-2的质粒之间的重组
J Bacteriol. 1976 Sep;127(3):1278-85. doi: 10.1128/jb.127.3.1278-1285.1976.
7
Resistance plasmids of Pseudomonas aeruginosa: change from conjugative to nonconjugative in a hospital population.铜绿假单胞菌的耐药质粒：在医院环境中的菌株群体中从接合型转变为非接合型
Antimicrob Agents Chemother. 1976 May;9(5):810-6. doi: 10.1128/AAC.9.5.810.
8
Pseudomonas aeruginosa R factors determining gentamicin plus carbenicillin resistance from patients with urinary tract colonizations.从尿路定植患者中分离出的决定庆大霉素加羧苄青霉素耐药性的铜绿假单胞菌R因子
Antimicrob Agents Chemother. 1975 Jan;7(1):64-8. doi: 10.1128/AAC.7.1.64.
9
Properties of the beta-lactamase specified by the Pseudomonas plasmid RPL11.由铜绿假单胞菌质粒RPL11所编码的β-内酰胺酶的特性
J Bacteriol. 1977 Oct;132(1):341-5. doi: 10.1128/jb.132.1.341-345.1977.
10
Pseudomonas aeruginosa strain isolated in France that carries a plasmid determining carbenicillin resistance.在法国分离出的携带决定羧苄青霉素抗性质粒的铜绿假单胞菌菌株。
Antimicrob Agents Chemother. 1977 Apr;11(4):589-93. doi: 10.1128/AAC.11.4.589.

本文引用的文献

1
Properties of R plasmids determining gentamicin resistance by acetylation in Pseudomonas aeruginosa.铜绿假单胞菌中通过乙酰化作用决定庆大霉素耐药性的R质粒特性
Antimicrob Agents Chemother. 1974 Sep;6(3):239-52. doi: 10.1128/AAC.6.3.239.
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Gentamicin resistance in Pseudomonas aeruginosa: R-factor-mediated resistance.铜绿假单胞菌对庆大霉素的耐药性：R 因子介导的耐药性。
Antimicrob Agents Chemother. 1974 Aug;6(2):191-9. doi: 10.1128/AAC.6.2.191.
3
Gentamicin-adenylyltransferase activity as a cause of gentamicin resistance in clinical isolates of Pseudomonas aeruginosa.庆大霉素腺苷酸转移酶活性是铜绿假单胞菌临床分离株中庆大霉素耐药的一个原因。
Antimicrob Agents Chemother. 1974 Jun;5(6):565-70. doi: 10.1128/AAC.5.6.565.
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Replication of R-factors in Proteus mirabilis: replication under relaxed control.奇异变形杆菌中R因子的复制：松弛控制下的复制
J Mol Biol. 1970 Aug;51(3):473-89. doi: 10.1016/0022-2836(70)90002-1.
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Antibiotic susceptibility testing by a standardized single disk method.采用标准化单纸片法进行抗生素敏感性试验。
Am J Clin Pathol. 1966 Apr;45(4):493-6.
6
R-factor mediated beta-lactamase in Pseudomonas aeruginosa.铜绿假单胞菌中R因子介导的β-内酰胺酶
Nature. 1970 Jun 13;226(5250):1054-6. doi: 10.1038/2261054a0.
7
New immunotype schema for Pseudomonas aeruginosa based on protective antigens.基于保护性抗原的铜绿假单胞菌新免疫分型方案。
J Bacteriol. 1969 May;98(2):835-6. doi: 10.1128/jb.98.2.835-836.1969.
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[Transferable resistance to gentamicin. I. Expression of the resistance character].[对庆大霉素的可转移抗性。I. 抗性特征的表达]
Ann Inst Pasteur (Paris). 1971 Dec;121(6):733-42.
9
Intergeneric transfer of a beta-lactamase gene between Ps. aeruginosa and E. coli.β-内酰胺酶基因在铜绿假单胞菌和大肠杆菌之间的属间转移。
Nature. 1970 Jun 6;226(5249):952-4. doi: 10.1038/226952a0.
10
Dissociation of a degradative plasmid aggregate in Pseudomonas.假单胞菌中降解性质粒聚集体的解离
J Bacteriol. 1974 Jun;118(3):815-20. doi: 10.1128/jb.118.3.815-820.1974.

RPL11，一种决定羧苄青霉素和庆大霉素抗性的铜绿假单胞菌R因子。

RPL11, an R factor of Pseudomonas aeruginosa determining carbenicillin and gentamicin resistance.

作者信息

Korfhagen T R, Loper J C

出版信息

Antimicrob Agents Chemother. 1975 Jan;7(1):69-73. doi: 10.1128/AAC.7.1.69.

DOI:10.1128/AAC.7.1.69
PMID:806259
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC429075/
Abstract

R factor RPL11 from Pseudomonas aeruginosa determines multiple drug resistance including resistance to gentamicin and carbenicillin. The host range and incompatibility properties of RPL11 are those of incompatibility group P-2. Strains harboring the factor are not altered with respect to the major immunotypes 1 through 7 of Parke-Davis, or with respect to pyocin type by using the 18 indicators of Jones and co-workers. Analytical ultracentrifugation of crude extracts of R factor-containing strains shows a band of satellite DNA with a buoyant density of 1.717 g/cm(3).

摘要

来自铜绿假单胞菌的R因子RPL11决定了多重耐药性，包括对庆大霉素和羧苄青霉素的耐药性。RPL11的宿主范围和不相容性特性属于不相容性P-2组。携带该因子的菌株在Parke-Davis的主要免疫型1至7方面，或在使用Jones及其同事的18种指示菌的情况下在绿脓菌素类型方面均未发生改变。对含有R因子的菌株粗提物进行分析超速离心，结果显示出一条卫星DNA带，其浮力密度为1.717 g/cm³。