OXA-2β-内酰胺酶与其他R质粒介导的β-内酰胺酶之间的免疫学比较。
Immunological comparison between OXA-2 beta-lactamase and those mediated by other R plasmids.
作者信息
Holland S, Dale J W
出版信息
Antimicrob Agents Chemother. 1985 Jun;27(6):989-91. doi: 10.1128/AAC.27.6.989.
Abstract
Antibodies to the OXA-2 beta-lactamase inhibited both OXA-2 and OXA-3 enzymes, but there was no effect on any other beta-lactamase. The cross-neutralization indicates considerable homology between the OXA-2 and OXA-3 enzymes and supports the suggestion that the OXA-3 beta-lactamase may have been derived from the OXA-2 gene via a deletion.
摘要
针对OXA - 2β - 内酰胺酶的抗体可抑制OXA - 2和OXA - 3酶，但对其他任何β - 内酰胺酶均无作用。这种交叉中和作用表明OXA - 2和OXA - 3酶之间存在相当程度的同源性，并支持了OXA - 3β - 内酰胺酶可能是通过缺失从OXA - 2基因衍生而来的观点。
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