Bousquet J, Bullinger M, Fayol C, Marquis P, Valentin B, Burtin B
Service des Maladies Respiratoires, Hôpital Arnaud de Villeneuve, Montpellier, France.
J Allergy Clin Immunol. 1994 Aug;94(2 Pt 1):182-8. doi: 10.1016/0091-6749(94)90038-8.
Perennial allergic rhinitis may impair social life. General scales of quality of life (QOL) are used to detect the importance of social life impairment, but the reliability and validity of QOL measures should be tested in patients with perennial allergic rhinitis. The extent to which QOL scores differ in patients with rhinitis and healthy subjects is unknown.
A cross-sectional study was carried out in 111 patients with moderate to severe perennial allergic rhinitis and 116 healthy subjects to assess the validity of a general QOL scale, the SF-36 Health Status Questionnaire. This scale is based on 36 items selected to represent nine health concepts (dimensions). The internal reliability of each dimension of the questionnaire was examined. The differences in QOL scores between patients with rhinitis and healthy subjects were studied.
Most QOL scores were highly reliable. There was a significant impairment in eight of nine QOL dimensions in patients with perennial allergic rhinitis in comparison with healthy subjects.
The SF-36 Health Status Questionnaire allows discrimination between patients with perennial allergic rhinitis and healthy subjects.
常年性变应性鼻炎可能会损害社交生活。生活质量(QOL)的通用量表用于检测社交生活受损的重要性,但QOL测量的可靠性和有效性应在常年性变应性鼻炎患者中进行测试。鼻炎患者与健康受试者的QOL得分差异程度尚不清楚。
对111例中重度常年性变应性鼻炎患者和116例健康受试者进行了一项横断面研究,以评估通用QOL量表SF-36健康状况问卷的有效性。该量表基于36个项目,这些项目被选来代表九个健康概念(维度)。检查了问卷各维度的内部可靠性。研究了鼻炎患者与健康受试者之间QOL得分的差异。
大多数QOL得分具有高度可靠性。与健康受试者相比,常年性变应性鼻炎患者的九个QOL维度中有八个存在显著损害。
SF-36健康状况问卷能够区分常年性变应性鼻炎患者和健康受试者。