Crawford A M, Montgomery G W, Pierson C A, Brown T, Dodds K G, Sunden S L, Henry H M, Ede A J, Swarbrick P A, Berryman T
Department of Biochemistry, University of Otago, Dunedin, New Zealand.
Genetics. 1994 Jun;137(2):573-9. doi: 10.1093/genetics/137.2.573.
Nineteen linkage groups containing a total of 52 markers have been identified in the sheep genome after typing large paternal half-sib families. The linkage groups range in size from 2 markers showing no recombination to a group containing 6 markers covering approximately 30 cM of the sheep genome. Thirteen of the groups have been assigned to a sheep chromosome. Three groups contain markers from bovine syntenic groups U2, U7 and U29, and one other group contains a marker that has been mapped only in humans. The remaining three groups are unassigned. This information will provide a useful foundation for a genetic linkage map of sheep.
在对大型父系半同胞家系进行分型后,已在绵羊基因组中鉴定出19个连锁群,共包含52个标记。连锁群的大小不一,从没有重组的2个标记到包含6个标记、覆盖约30厘摩绵羊基因组的一个连锁群。其中13个连锁群已被定位到绵羊的一条染色体上。三个连锁群包含来自牛同线群U2、U7和U29的标记,另一个连锁群包含一个仅在人类中定位的标记。其余三个连锁群未被定位。这些信息将为绵羊的遗传连锁图谱提供有用的基础。