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高渗腹膜透析液对中性粒细胞超氧化物生成的影响。

Effects of hypertonic peritoneal dialysis solutions on neutrophil superoxide production.

作者信息

Zhou F Q, Manahan F J, Yu A W, Rahman M A, Nawab Z M, Fisher K A, Ing T S

机构信息

Department of Medicine, Veterans Administration Hospital, Hines, IL 60141.

出版信息

Artif Organs. 1990 Dec;14(6):410-2. doi: 10.1111/j.1525-1594.1990.tb02995.x.

Abstract

Superoxide produced by neutrophils plays an important role in the killing of bacterial pathogens. The effects of glucose-containing peritoneal dialysis solutions on superoxide production by canine and human neutrophils were studied. A significant decrement in superoxide generation was noted with the 2.27% and 3.86% glucose solutions. The results suggest that hypertonic peritoneal dialysis solutions curtail neutrophil superoxide generation.

摘要

中性粒细胞产生的超氧化物在杀灭细菌病原体中起重要作用。研究了含葡萄糖的腹膜透析液对犬和人中性粒细胞产生超氧化物的影响。使用2.27%和3.86%的葡萄糖溶液时,超氧化物生成量显著减少。结果表明,高渗腹膜透析液可减少中性粒细胞超氧化物的生成。

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