Stiffler P W, Lerner S A, Bohnhoff M, Morello J A
J Bacteriol. 1975 Jun;122(3):1293-300. doi: 10.1128/jb.122.3.1293-1300.1975.
Two different sizes of circular covalently closed deoxyribonucleic acid plasmids have been identified in four independent clinical isolates of Neisseria gonorrhoeae. All four strains contained a small plasmid with a molecular weight of 2.8 X 10-6 and two of the four stains also contained a large plasmid with a molecular weight of 24.5 X 10-6. The avirulent derivative of each of these four strains had the same plasmid complement as its virulent parent. There was no correlation between the presence of these plasmids and antibiotic resistance, piliation, and colony type associated with virulence, or ability to grow without seven specific amino acid supplements.
在四株独立的淋病奈瑟菌临床分离株中鉴定出了两种不同大小的环状共价闭合脱氧核糖核酸质粒。所有四株菌株都含有一个分子量为2.8×10⁻⁶ 的小质粒，四株中的两株还含有一个分子量为24.5×10⁻⁶ 的大质粒。这四株菌株中每一株的无毒衍生物都与其有毒亲代具有相同的质粒组成。这些质粒的存在与抗生素抗性、菌毛、与毒力相关的菌落类型或在无七种特定氨基酸补充剂的情况下生长的能力之间没有相关性。
