Trick G L
School of Optometry, University of Montreal, Quebec, Canada.
Doc Ophthalmol. 1993;85(2):125-33. doi: 10.1007/BF01371128.
Color vision (desaturated D-15), contrast sensitivity (Vistech 6500) and pattern electroretinograms (transient and steady state) were measured in nine patients with diagnosed normotensive glaucoma. Results were compared to those from visually normal controls subjects (n = 73) and patients with primary open-angle glaucoma (n = 51). Patients with normotensive glaucoma exhibited significant contrast sensitivity and pattern electroretinogram deficits similar to those evident in patients with primary open-angle glaucoma. However, patients with normotensive glaucoma exhibited significantly better color vision than did patients with primary open-angle glaucoma. These results indicate that the pattern of visual impairment associated normotensive glaucoma and primary open-angle glaucoma is not identical. Different pathologic mechanisms mediating visual loss in the two diseases could explain these differences.
对9例已确诊的正常眼压性青光眼患者进行了色觉(不饱和D-15)、对比敏感度(Vistech 6500)和图形视网膜电图(瞬态和稳态)测量。将结果与视力正常的对照受试者(n = 73)和原发性开角型青光眼患者(n = 51)的结果进行比较。正常眼压性青光眼患者表现出与原发性开角型青光眼患者相似的显著对比敏感度和图形视网膜电图缺陷。然而,正常眼压性青光眼患者的色觉明显优于原发性开角型青光眼患者。这些结果表明,与正常眼压性青光眼和原发性开角型青光眼相关的视力损害模式并不相同。两种疾病中导致视力丧失的不同病理机制可以解释这些差异。