Santy P A, Faulk D M, Davis J R
Department of Psychiatry and Behavioral Sciences, University of Texas Medical Branch, Galveston 77555-0428.
J Clin Pharmacol. 1994 May;34(5):535-42. doi: 10.1002/j.1552-4604.1994.tb04997.x.
In June, 1990, a workshop was put together at NASA/Johnson Space Center to address difficulties the astronauts were having in adjusting their wake and sleep schedule, both immediately before and during Space Shuttle missions. The workshop members, prominent investigators in human circadian research, developed a number of strategies by which astronauts could tackle the problem of circadian adaptation within the demanding timetable of a Space Shuttle mission. The strategies included both abrupt and gradual methods, and some approaches used artificial "very bright lights" to reset the physiologic circadian pacemaker. The strategies have since been operationally implemented on Space Shuttle flights, with good success. This is a report of the problems addressed by the workshop and its recommendations.
1990年6月，美国国家航空航天局约翰逊航天中心举办了一次研讨会，以解决宇航员在航天飞机任务前及任务期间调整作息时间表时遇到的困难。研讨会成员均是人类昼夜节律研究领域的杰出研究者，他们制定了一系列策略，宇航员可据此在航天飞机任务紧张的时间表内应对昼夜节律适应问题。这些策略包括突然调整和逐步调整的方法，一些方法还使用人工“强光”来重置生理昼夜节律起搏器。此后，这些策略已在航天飞机飞行任务中实际应用，并取得了良好成效。本文报告了研讨会上所探讨的问题及其建议。
