Denis P, Charpentier D, Roudier M, Lemaire J C, Levin N, Nguyen-Khoa J L
Service d'Ophtalmologie, Centre Hospitalier Universitaire de la Guadeloupe, Pointe-à-Pitre.
J Fr Ophtalmol. 1994;17(5):366-9.
We describe the clinical and histopathological findings of a conjunctival squamous cell carcinoma occurring in a patient with acquired immunodeficiency syndrome (AIDS). The excisional biopsy specimen disclosed a papillar, well differentiated and mature squamous cell carcinoma with microinvasion. The biopsy was studied for the presence of Human papilloma virus DNA by using in situ hybridization but no signal was demonstrated in any part of the tumour. Although Kaposi's sarcoma and non-Hodgkin's lymphomas are the most common malignancies reported in AIDS, squamous cell carcinomas may be encountered in the disease. Underlying infection with the human immunodeficiency virus should be considered when conjunctival localization of such malignancies is observed.
我们描述了一名获得性免疫缺陷综合征（AIDS）患者发生的结膜鳞状细胞癌的临床和组织病理学表现。切除活检标本显示为乳头状、高分化且成熟的鳞状细胞癌伴微浸润。通过原位杂交对活检标本进行人乳头瘤病毒DNA检测，但肿瘤任何部位均未显示信号。尽管卡波西肉瘤和非霍奇金淋巴瘤是AIDS中报道的最常见恶性肿瘤，但该疾病中也可能出现鳞状细胞癌。当观察到此类恶性肿瘤发生于结膜时，应考虑潜在的人类免疫缺陷病毒感染。
