Björck L, Rosén C, Marshall V, Reiter B
Appl Microbiol. 1975 Aug;30(2):199-204. doi: 10.1128/am.30.2.199-204.1975.
Products of thiocyanate oxidation by lactoperoxidase inhibit gram-positive bacteria that produce peroxide. We found these products to be bactericidal for such gram-negative bacteria as Pseudomonas species and Escherichia coli, provided peroxide is supplied exogenously by glucose oxidase and glucose. By the use of immobilized glucose oxidase the bacterial agent was shown to be dialyzable, destroyed by heat and counteracted, or destroyed by reducing agents. Because the system is active against a number of gram-negative bacteria isolated from milk, it may possibly be exploited to increase the keeping quality of raw milk.
乳过氧化物酶催化硫氰酸盐氧化产生的产物可抑制能产生过氧化物的革兰氏阳性菌。我们发现，若通过葡萄糖氧化酶和葡萄糖外源提供过氧化物，这些产物对铜绿假单胞菌和大肠杆菌等革兰氏阴性菌具有杀菌作用。利用固定化葡萄糖氧化酶表明，该细菌制剂具有可透析性，受热会被破坏，可被还原剂中和或破坏。由于该系统对从牛奶中分离出的多种革兰氏阴性菌具有活性，因此有可能用于提高生牛奶的保存质量。
