Johnston M, Andrews S, Brinkman R, Cooper J, Ding H, Dover J, Du Z, Favello A, Fulton L, Gattung S
Department of Genetics, Washington University School of Medicine, St. Louis, MO 63110.
Science. 1994 Sep 30;265(5181):2077-82. doi: 10.1126/science.8091229.
The complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII reveals that it contains 269 predicted or known genes (300 base pairs or larger). Fifty-nine of these genes (22 percent) were previously identified. Of the 210 novel genes, 65 are predicted to encode proteins that are similar to other proteins of known or predicted function. Sixteen genes appear to be relatively recently duplicated. On average, there is one gene approximately every 2 kilobases. Although the coding density and base composition across the chromosome are not uniform, no regular pattern of variation is apparent.
酿酒酵母第八条染色体的完整核苷酸序列显示，它包含269个预测或已知基因（300个碱基对或更长）。其中59个基因（22%）先前已被鉴定。在210个新基因中，65个预计编码与已知或预测功能的其他蛋白质相似的蛋白质。16个基因似乎是相对近期复制的。平均每2千碱基大约有一个基因。尽管整个染色体的编码密度和碱基组成并不均匀，但没有明显的规则变化模式。
