Serrou B, Senelar R
C R Acad Hebd Seances Acad Sci D. 1975 Feb 24;280(8):1035-7.
Thymocytes cultured in medium containing human chorionic gonadotrophin hormone (HCG) are capable of blocking the response of peripheral splenic lymphocytes to mitogens in medium containing no HCG. This effect is not due to cytotoxicity. Our results suggest that the inhibition of lymphocyte response by serum from gestating subjects could be due to the presence of large quantities of HCG. This would be, at least partially, and by a direct or indirect mechanism, responsible for foetal acceptance by the mother. The implications of these findings in cancerology are manifest.
在含有人绒毛膜促性腺激素（HCG）的培养基中培养的胸腺细胞能够阻断外周脾淋巴细胞在不含HCG的培养基中对丝裂原的反应。这种效应并非由于细胞毒性。我们的结果表明，妊娠受试者血清对淋巴细胞反应的抑制可能是由于大量HCG的存在。这至少部分地通过直接或间接机制，促成母亲对胎儿的接纳。这些发现在肿瘤学中的意义是显而易见的。
