Martinez F D, Wright A L, Taussig L M
Department of Pediatrics, University of Arizona College of Medicine, Tucson.
Am J Public Health. 1994 Sep;84(9):1489-91. doi: 10.2105/ajph.84.9.1489.
We examined the relationship of paternal smoking habits to birthweight in a cohort of infants enrolled at birth (n = 1219). To assess validity of parental smoking reports, cord serum levels of cotinine were measured in 175 newborns. A mean birthweight deficit of 88 g was found in newborns of nonsmoking mothers whose fathers smoked more than 20 cigarettes/day. Only 2 of 138 newborns whose mothers said they were nonsmokers had cotinine levels indicating that their mothers were active smokers. Among infants of nonsmoking mothers, detectability of cotinine in cord blood was significantly correlated with the number of cigarettes smoked daily by fathers. These data suggest that fetal growth may be adversely affected when the mother is passively exposed to tobacco smoke during pregnancy.
我们在一组出生时登记入组的婴儿（n = 1219）中研究了父亲吸烟习惯与出生体重之间的关系。为评估父母吸烟报告的有效性，我们测量了175名新生儿脐带血中的可替宁水平。在母亲不吸烟但父亲每天吸烟超过20支的新生儿中，发现平均出生体重不足88克。在138名母亲称自己不吸烟的新生儿中，只有2名新生儿的可替宁水平表明其母亲是现吸烟者。在母亲不吸烟的婴儿中，脐带血中可替宁的可检测性与父亲每日吸烟量显著相关。这些数据表明，孕期母亲被动接触烟草烟雾可能会对胎儿生长产生不利影响。
