Gremse D A, Boudreaux C W, Manci E A
Division of Pediatric Gastroenterology and Nutrition, University of South Alabama College of Medicine, Mobile.
Gastroenterology. 1993 Mar;104(3):906-9. doi: 10.1016/0016-5085(93)91030-l.
Collagenous colitis, a disorder characterized by increased subepithelial collagen deposition associated with an inflammatory infiltrate in the lamina propria, has been reported infrequently in children. An 8-year-old girl with collagenous colitis is described who presented with chronic watery diarrhea and abdominal pain. Biopsy specimens of the colonic mucosa showed the pathological features of collagenous colitis. The patient's symptoms resolved following corticosteroid therapy. Collagenous colitis should be considered in the differential diagnosis of children with chronic diarrhea.
胶原性结肠炎是一种以黏膜下层胶原沉积增加并伴有固有层炎症浸润为特征的疾病,在儿童中鲜有报道。本文描述了一名8岁患胶原性结肠炎的女孩,她表现为慢性水样腹泻和腹痛。结肠黏膜活检标本显示出胶原性结肠炎的病理特征。该患者在接受皮质类固醇治疗后症状缓解。对于患有慢性腹泻的儿童,鉴别诊断时应考虑胶原性结肠炎。