Reed K D, Moore F M, Geiger G E, Stemper M E
Microbiology Section, Marshfield Laboratories, Wisconsin 54449.
Clin Infect Dis. 1993 Mar;16(3):384-7. doi: 10.1093/clind/16.3.384.
We report a case of sporotrichosis in a veterinarian who acquired the infection from a cat. Transmission was confirmed at the genetic level by demonstration that the two clinical isolates of Sporothrix schenckii had identical restriction-fragment-length profiles of whole-cell DNA. Review of the literature indicates that zoonotic transmission of sporotrichosis is rare and is virtually always associated with direct contact with an infected cat. Exposure to the large number of fungal organisms present in skin lesions of cats with sporotrichosis can result in transmission of infection to humans even without an associated penetrating injury. Since veterinarians and their assistants are at greatest risk, awareness of this mode of transmission and proper use of gloves when caring for cats with cutaneous ulcers should prevent most cases.
我们报告一例兽医患孢子丝菌病的病例，该兽医从一只猫身上感染了此病。通过证明申克孢子丝菌的两个临床分离株具有相同的全细胞DNA限制性片段长度图谱，在基因水平上证实了传播。文献回顾表明，孢子丝菌病的人畜共患病传播很少见，几乎总是与直接接触受感染的猫有关。接触患有孢子丝菌病的猫皮肤病变中存在的大量真菌生物体，即使没有相关的穿透性损伤，也可能导致感染传播给人类。由于兽医及其助手面临的风险最大，了解这种传播方式并在护理有皮肤溃疡的猫时正确使用手套应可预防大多数病例。
