Pereira Sandro A, Menezes Rodrigo C, Gremião Isabella D F, Silva Jéssica N, Honse Carla de O, Figueiredo Fabiano B, da Silva Denise T, Kitada Amanda A Braga, dos Reis Erica G, Schubach Tânia M P
Laboratório de Pesquisa Clínica em Dermatozoonoses em Animais Domésticos, Instituto de Pesquisa Clínica Evandro Chagas, Fundação Oswaldo Cruz, Avenida Brasil, 4365. Manguinhos, Rio de Janeiro, RJ 21040-900, Brazil.
J Feline Med Surg. 2011 Apr;13(4):220-3. doi: 10.1016/j.jfms.2010.10.007. Epub 2010 Dec 4.
Sporotrichosis is caused by Sporothrix schenckii. The cat is the animal species most affected by this mycosis and plays an important role in the zoonotic transmission of this disease. The definitive diagnosis is made by isolation of the fungus in culture; however, cytopathological examination is frequently used in cats. Medical records from cats treated at Instituto de Pesquisa Clínica Evandro Chagas/Fiocruz, Rio de Janeiro, Brazil, between 2004 and 2006 were reviewed. Criteria for inclusion were a diagnosis by isolation of S schenckii in culture and cytopathological examination of the same lesion as that used for collection of the culture material. Eight hundred and six cats were included in the study. Yeast-like structures suggestive of S schenckii were observed in 636 cases. The sensitivity of the method was 78.9%. Its practicality, low cost and sensitivity validate cytopathology as a safe technique for the presumptive diagnosis of sporotrichosis in cats.
孢子丝菌病由申克孢子丝菌引起。猫是受这种真菌病影响最严重的动物物种,在该疾病的人畜共患病传播中起重要作用。确诊需通过在培养基中分离出真菌;然而,细胞病理学检查在猫中经常使用。对2004年至2006年期间在巴西里约热内卢的埃万德罗·查加斯临床研究所/巴西奥斯瓦尔多·克鲁兹基金会接受治疗的猫的病历进行了回顾。纳入标准为通过在培养基中分离出申克孢子丝菌进行诊断,以及对用于采集培养基材料的同一病变进行细胞病理学检查。806只猫被纳入该研究。636例病例中观察到提示申克孢子丝菌的酵母样结构。该方法的敏感性为78.9%。其实用性、低成本和敏感性证实细胞病理学是一种用于猫孢子丝菌病推定诊断的安全技术。