Abdallah R M, Ghazy N M, El-Sebakhy N A, Pirillo A, Verotta L
Faculty of Pharmacy, University of Alexandria, Egypt.
Pharmazie. 1993 Jun;48(6):452-4.
Four cycloartane triterpene oligoglycosides were isolated from the n-butanol extract of the aerial parts of Astragalus spinosus Vahl. (Leguminosae). They were identified as astragaloside I (1), isoastragaloside I (2), astragaloside IV (4) and cycloastragenol 6-O-glucoside (5) on the basis of comparing their m.p.'s, 1H NMR and 13C NMR spectra and chromatographic patterns with the data given in the literature. The results of AIDS antiviral and antitumor screening of the major component, astragaloside II (3), are dealt with.
从棘豆黄芪（豆科）地上部分的正丁醇提取物中分离得到了四种环阿尔廷烷三萜寡糖苷。通过将它们的熔点、¹H NMR和¹³C NMR光谱以及色谱图与文献中给出的数据进行比较，鉴定出它们分别为黄芪苷I（1）、异黄芪苷I（2）、黄芪苷IV（4）和环黄芪醇6-O-葡萄糖苷（5）。文中还讨论了主要成分黄芪苷II（3）的抗艾滋病病毒和抗肿瘤筛选结果。
