从药用植物蓝花丹中分离出两种具有抗流感病毒活性的新木脂素。

Two new lignans with activity against influenza virus from the medicinal plant Rhinacanthus nasutus.

作者信息

Kernan M R, Sendl A, Chen J L, Jolad S D, Blanc P, Murphy J T, Stoddart C A, Nanakorn W, Balick M J, Rozhon E J

机构信息

Shaman Pharmaceuticals, South San Francisco, California 94080-4812, USA.

出版信息

J Nat Prod. 1997 Jun;60(6):635-7. doi: 10.1021/np960613i.

DOI:10.1021/np960613i

PMID:9214738

Abstract

Two new lignans, rhinacanthin E (1) and rhinacanthin F (2), were isolated from the aerial parts of the plant Rhinacanthus nasutus. Their structures were established by detailed spectroscopic analysis. These compounds show significant antiviral activity against influenza virus type A.

摘要

从长穗爵床的地上部分分离出两种新的木脂素，爵床素E（1）和爵床素F（2）。通过详细的光谱分析确定了它们的结构。这些化合物对甲型流感病毒显示出显著的抗病毒活性。