三种落基山斑疹热疫苗的比较。
Comparison of three rocky mountain spotted fever vaccines.
作者信息
Kenyon R H, Sammons L S, Pedersen C E
出版信息
J Clin Microbiol. 1975 Oct;2(4):300-4. doi: 10.1128/jcm.2.4.300-304.1975.
Abstract
Growth of Rocky Mountain spotted fever (RMSF) rickettsiae in duck embryo cell (DEC) cultures and chicken embryo cell (CEC) cultures was evaluated. Experimental lots of duck embryo cell- and chicken embryo cell-grown Rocky Mountain spotted fever vaccines and a commercial lot of yolk sac-grown vaccine were compared for protective efficacy in rhesus monkeys. Incidence and magnitude of antibody response, febrile response, and rickettsemia, as well as incidence of fatalities, suggested that both cell culture-derived vaccines were more immunogenic than the yolk sac-grown vaccine.
摘要
对落基山斑疹热立克次体在鸭胚细胞（DEC）培养物和鸡胚细胞（CEC）培养物中的生长情况进行了评估。比较了实验批次的鸭胚细胞培养和鸡胚细胞培养的落基山斑疹热疫苗以及一批商业卵黄囊培养疫苗在恒河猴中的保护效力。抗体反应的发生率和强度、发热反应、立克次体血症以及死亡率表明，两种细胞培养衍生疫苗比卵黄囊培养疫苗更具免疫原性。
相似文献
1
Comparison of three rocky mountain spotted fever vaccines.三种落基山斑疹热疫苗的比较。
J Clin Microbiol. 1975 Oct;2(4):300-4. doi: 10.1128/jcm.2.4.300-304.1975.
2
Effect of vaccination schedule on immune response of Macaca mulatta to cell culture-grown Rocky Mountain spotted fever vaccine.疫苗接种程序对猕猴针对细胞培养的落基山斑疹热疫苗免疫反应的影响。
J Clin Microbiol. 1976 Sep;4(3):253-7. doi: 10.1128/jcm.4.3.253-257.1976.
3
Preparation of Rocky Mountain spotted fever vaccine suitable for human immunization.制备适用于人体免疫的落基山斑疹热疫苗。
J Clin Microbiol. 1975 Jun;1(6):500-3. doi: 10.1128/jcm.1.6.500-503.1975.
4
Evaluation of a killed Rocky Mountain spotted fever vaccine in cynomolgus monkeys.食蟹猴中一种灭活落基山斑疹热疫苗的评估
J Clin Microbiol. 1979 Nov;10(5):719-23. doi: 10.1128/jcm.10.5.719-723.1979.
5
Rocky Mountain spotted fever vaccine: a regional need.落基山斑疹热疫苗：一项地区需求。
South Med J. 1984 Apr;77(4):447-9. doi: 10.1097/00007611-198404000-00009.
6
Preparation of vaccines for Rocky Mountain spotted fever from rickettsiae propagated in cell culture.用在细胞培养中繁殖的立克次氏体制备落基山斑疹热疫苗。
J Infect Dis. 1972 Feb;125(2):146-52. doi: 10.1093/infdis/125.2.146.
7
New assay of protective activity of Rocky Mountain spotted fever vaccines.落基山斑疹热疫苗保护活性的新检测方法。
J Clin Microbiol. 1976 Sep;4(3):309-11. doi: 10.1128/jcm.4.3.309-311.1976.
8
Reactogenicity, immunogenicity, and efficacy of a chick embryo cell-derived vaccine for Rocky Mountain spotted fever.一种鸡胚细胞源性落基山斑疹热疫苗的反应原性、免疫原性和效力
J Infect Dis. 1983 Nov;148(5):922-30. doi: 10.1093/infdis/148.5.922.
9
Rocky Mountain spotted fever vaccine in an animal model.落基山斑疹热疫苗在动物模型中的研究
J Clin Microbiol. 1983 Aug;18(2):321-6. doi: 10.1128/jcm.18.2.321-326.1983.
10
Rickettsia rickettsii Whole-Cell Antigens Offer Protection against Rocky Mountain Spotted Fever in the Canine Host.恙虫病东方体全细胞抗原在犬宿主中提供对落矶山斑点热的保护。
Infect Immun. 2019 Jan 24;87(2). doi: 10.1128/IAI.00628-18. Print 2019 Feb.
引用本文的文献
1
Vaccination-induced neutralizing antibodies in immunocompetent hosts correlate with protection against rickettsiae.免疫功能正常宿主中疫苗接种诱导的中和抗体与抗立克次氏体的保护作用相关。
NPJ Vaccines. 2025 Aug 1;10(1):180. doi: 10.1038/s41541-025-01228-4.
2
Vaccine development: obligate intracellular bacteria new tools, old pathogens: the current state of vaccines against obligate intracellular bacteria.疫苗开发：必需细胞内细菌的新工具，旧病原体：针对必需细胞内细菌的疫苗的现状。
Front Cell Infect Microbiol. 2024 Mar 19;14:1282183. doi: 10.3389/fcimb.2024.1282183. eCollection 2024.
3
A Vaccine for Canine Rocky Mountain Spotted Fever: An Unmet One Health Need.一种用于犬类落基山斑疹热的疫苗：一项未满足的“同一健康”需求。
Vaccines (Basel). 2022 Sep 28;10(10):1626. doi: 10.3390/vaccines10101626.
4
Vaccine Design and Vaccination Strategies against Rickettsiae.针对立克次氏体的疫苗设计与接种策略
Vaccines (Basel). 2021 Aug 12;9(8):896. doi: 10.3390/vaccines9080896.
5
The neglected challenge: Vaccination against rickettsiae.被忽视的挑战：立克次氏体疫苗接种。
PLoS Negl Trop Dis. 2020 Oct 22;14(10):e0008704. doi: 10.1371/journal.pntd.0008704. eCollection 2020 Oct.
6
Phenotype of the anti-Rickettsia CD8(+) T cell response suggests cellular correlates of protection for the assessment of novel antigens.抗立克次体CD8(+) T细胞反应的表型提示了用于评估新型抗原的保护性细胞关联因素。
Vaccine. 2014 Sep 3;32(39):4960-7. doi: 10.1016/j.vaccine.2014.07.032. Epub 2014 Jul 18.
7
Adherence to and invasion of host cells by spotted Fever group rickettsia species.斑点热群立克次体对宿主细胞的黏附和侵袭
Front Microbiol. 2010 Dec 20;1:139. doi: 10.3389/fmicb.2010.00139. eCollection 2010.
8
Molecular basis of immunity to rickettsial infection conferred through outer membrane protein B.通过外膜蛋白 B 赋予对立克次氏体感染的免疫的分子基础。
Infect Immun. 2011 Jun;79(6):2303-13. doi: 10.1128/IAI.01324-10. Epub 2011 Mar 28.
9
The realities of biodefense vaccines against Rickettsia.针对立克次氏体的生物防御疫苗的实际情况。
Vaccine. 2009 Nov 5;27 Suppl 4(Suppl 4):D52-5. doi: 10.1016/j.vaccine.2009.07.045.
10
Effect of vaccination schedule on immune response of Macaca mulatta to cell culture-grown Rocky Mountain spotted fever vaccine.疫苗接种程序对猕猴针对细胞培养的落基山斑疹热疫苗免疫反应的影响。
J Clin Microbiol. 1976 Sep;4(3):253-7. doi: 10.1128/jcm.4.3.253-257.1976.
本文引用的文献
1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
2
Plaque assay for Rickettsia rickettsii.立氏立克次体的噬斑测定
J Bacteriol. 1969 May;98(2):398-402. doi: 10.1128/jb.98.2.398-402.1969.
3
Method for counting Rickettsiae and Chlamydiae in purified suspensions.纯化悬浮液中立克次氏体和衣原体的计数方法。
J Bacteriol. 1968 Jan;95(1):259-61. doi: 10.1128/jb.95.1.259-261.1968.
4
Plaque formation in tissue cultures by Rickettsia rickettsi isolated directly from whole blood and tick hemolymph.从全血和蜱血淋巴中直接分离出的立氏立克次体在组织培养中形成斑块。
Infect Immun. 1972 Nov;6(5):736-8. doi: 10.1128/iai.6.5.736-738.1972.
5
Preparation of vaccines for Rocky Mountain spotted fever from rickettsiae propagated in cell culture.用在细胞培养中繁殖的立克次氏体制备落基山斑疹热疫苗。
J Infect Dis. 1972 Feb;125(2):146-52. doi: 10.1093/infdis/125.2.146.
6
A microagglutination technique for detection and measurement of rickettsial antibodies.一种用于检测和测量立克次氏体抗体的微量凝集技术。
Acta Virol. 1969 Jan;13(1):60-6.
7
Rocky Mountain spotted fever: a comparative study of the active immunity induced by inactivated and viable pathogenic Rickettsia rickettsii.落基山斑疹热：对灭活和活立克次氏体立克次体诱导的主动免疫的比较研究
J Infect Dis. 1973 Sep;128(3):340-4. doi: 10.1093/infdis/128.3.340.
8
Preparation of Rocky Mountain spotted fever vaccine suitable for human immunization.制备适用于人体免疫的落基山斑疹热疫苗。
J Clin Microbiol. 1975 Jun;1(6):500-3. doi: 10.1128/jcm.1.6.500-503.1975.
Zotero 插件