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对泌尿外科肿瘤免疫诊断的一项贡献。

A contribution to immunological tumour diagnostics in urology.

作者信息

Günther M, Friedrich A, Erdmann T, Jenssen H L, Werner H, Seyfarth M, Köhler H

出版信息

Int Urol Nephrol. 1978;10(2):111-5. doi: 10.1007/BF02082130.

Abstract

Fifty-four patients with malignant and other diseases of the urinary bladder and the prostate were examined for lymphocyte sensitization by means of electrophoretic mobility test (EM test). In this antigens from brain tissue (EF) and from malignomas of kidney, urinary bladder and prostate were used. Positive HEP values were obtained in 40 patients out of 42 with malignant tumours and in 5 patients out of 12 with other kidney diseases. With the corresponding tumour-associated antigens (TAA) in the EM-test, the histological tumour diagnosis could be confirmed in every case. Positive findings after using EF as well as the corresponding TAA are with great probability an indication of a malignant disease.

摘要

对54例患有膀胱和前列腺恶性及其他疾病的患者,通过电泳迁移率试验(EM试验)检测淋巴细胞致敏情况。在该试验中,使用了脑组织抗原(EF)以及肾脏、膀胱和前列腺恶性肿瘤的抗原。42例恶性肿瘤患者中有40例获得了阳性HEP值,12例患有其他肾脏疾病的患者中有5例获得阳性HEP值。在EM试验中,使用相应的肿瘤相关抗原(TAA),在每种情况下都能确诊组织学肿瘤诊断。使用EF以及相应的TAA后得到的阳性结果极有可能表明患有恶性疾病。

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