Corrao G, Busellu G, Valenti M, Lepore A R, Sconci V, Casacchia M, di Orio F
Epidemiologic Research Centre, School of Medicine, University of L'Aquila, Italy.
Soc Psychiatry Psychiatr Epidemiol. 1993 Nov;28(6):304-8. doi: 10.1007/BF00795912.
We carried out a population-based prevalence study to assess the association between the presence of alcohol-related problems within the family and the risk of disorders in the children's global functioning level. We enrolled 394 children attending nursery, primary and secondary schools and their parents living in two municipalities in Central Italy. Alcohol-related problems within the family were reported by registered records obtained from general practitioners and teachers, who were considered as preference raters. The children's level of functioning was assessed by teachers, who attributed to each school child a score according to the Children Global Assessment Scale (CGAS). The number of reports of alcohol-related problems within the family and the CGAS scores were considered, respectively, as independent and dependent variables in a multiple logistic regression model for ordinal outcome variables. The children's sex and age, and the age of their parents, the duration of the parents' education and family size were considered as covariates. We found a strong association between a poor level of functioning in the children in the social environment and alcohol-related problems within the family. The prevalence odds ratio (and 95% confidence interval) decreased from 0.5 (range 0.2-1.3) for children whose families were reported by one rater to 0.4 (range 0.2-0.8) for children whose families were reported by two raters, the non-reported families being the reference category, suggesting that the level of functioning of the child decreased as reports of alcohol-related problems in the family increased.
我们开展了一项基于人群的患病率研究,以评估家庭中与酒精相关问题的存在与儿童整体功能水平障碍风险之间的关联。我们纳入了居住在意大利中部两个市镇的394名就读于幼儿园、小学和中学的儿童及其父母。家庭中与酒精相关的问题通过从全科医生和教师处获得的登记记录报告,他们被视为首选评估者。儿童的功能水平由教师评估,教师根据儿童整体评估量表(CGAS)为每个学童打分。在一个用于有序结局变量的多重逻辑回归模型中,分别将家庭中与酒精相关问题的报告数量和CGAS分数视为自变量和因变量。儿童的性别和年龄、父母的年龄、父母受教育的时长以及家庭规模被视为协变量。我们发现儿童在社会环境中的功能水平较差与家庭中与酒精相关的问题之间存在很强的关联。患病率比值比(及95%置信区间)从一个评估者报告有问题的家庭中的儿童的0.5(范围0.2 - 1.3)降至两个评估者报告有问题的家庭中的儿童的0.4(范围0.2 - 0.8),未报告有问题的家庭作为参照类别,这表明随着家庭中与酒精相关问题报告的增加,儿童的功能水平下降。