Sommer H, Koenen H
Medizinische Universitätsklinik Würzburg.
Med Klin (Munich). 1994 Jan 15;89(1):14-7.
We studied the course and particularly the social consequences of Crohn's disease (n = 107) and ulcerative colitis extending beyond the sigmoid colon (n = 22) during the first 6.1 respectively 6.3 years after onset.
Under common treatment, the disease activity decreased and the body mass index increased significantly in the majority of patients, but about 30% of them reached no continuous remission. The professional training was delayed in 23% of patients with Crohn's disease and 9% of those with ulcerative colitis. However, by objective datas and in the patients' own opinion the effect of both diseases on the professional qualification and occupational status which were reached in the end was small. The percentage of partly occupied patients and those without work compared to that of healthy ones. 11% of patients with Crohn's disease and 14% with ulcerative colitis had to retire prematurely. The patients' family status and the number of their children matched largely that of healthy men and women of same age.
我们分别对107例克罗恩病患者和22例病变超出乙状结肠的溃疡性结肠炎患者在发病后的头6.1年和6.3年期间的病程，尤其是社会后果进行了研究。
在常规治疗下，大多数患者的疾病活动度降低，体重指数显著增加，但约30%的患者未实现持续缓解。23%的克罗恩病患者和9%的溃疡性结肠炎患者的职业培训被推迟。然而，根据客观数据以及患者自身的看法，这两种疾病最终对职业资格和职业地位的影响较小。部分就业患者和无工作患者与健康人群的比例。11%的克罗恩病患者和14%的溃疡性结肠炎患者不得不提前退休。患者的家庭状况和子女数量与同龄健康男性和女性基本相当。
