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The sequence of a 12 kb fragment on the left arm of yeast chromosome XI reveals five new open reading frames, including a zinc finger protein and a homolog of the UDP-glucose pyrophosphorylase from potato.

作者信息

Purnelle B, Skala J, Van Dyck L, Goffeau A

机构信息

Unité de Biochimie Physiologique, Université Catholique de Louvain, Louvain-la-Neuve, Belgium.

出版信息

Yeast. 1992 Nov;8(11):977-86. doi: 10.1002/yea.320081108.

DOI:10.1002/yea.320081108
PMID:1481573
Abstract

We report the sequence of a 12,399 bp DNA fragment from the left arm of Saccharomyces cerevisiae chromosome XI. This fragment is located between the genetic loci mif2 and mak11. We have detected five new open reading frames (ORFs) longer than 300 bp provisionally called YKL248 to YKL252. One of them, YKL248 encodes a homolog of the UDP-glucose pyrophosphorylase from potato. The product of YKL251 contains the consensus for zinc binding proteins, similar to those of a number of fungal transcriptional activators. The three other ORFs do not show significant homology to known protein.

摘要

相似文献

1
The sequence of a 12 kb fragment on the left arm of yeast chromosome XI reveals five new open reading frames, including a zinc finger protein and a homolog of the UDP-glucose pyrophosphorylase from potato.
Yeast. 1992 Nov;8(11):977-86. doi: 10.1002/yea.320081108.
2
The complete sequence of a 33 kb fragment on the right arm of chromosome II from Saccharomyces cerevisiae reveals 16 open reading frames, including ten new open reading frames, five previously identified genes and a homologue of the SCO1 gene.来自酿酒酵母二号染色体右臂上一个33 kb片段的完整序列揭示了16个开放阅读框，其中包括10个新的开放阅读框、5个先前已鉴定的基因以及SCO1基因的一个同源物。
Yeast. 1994 Apr;10 Suppl A:S75-80. doi: 10.1002/yea.320100010.
3
DNA sequencing of a 36.2 kb fragment located between the FAS1 and LAP loci of chromosome XI of Saccharomyces cerevisiae.对酿酒酵母11号染色体上位于FAS1和LAP基因座之间的一个36.2 kb片段进行DNA测序。
Yeast. 1994 Apr;10 Suppl A:S35-40. doi: 10.1002/yea.320100005.
4
The sequence of a 9.3 kb segment located on the left arm of the yeast chromosome XI reveals five open reading frames including the CCE1 gene and putative products related to MYO2 and to the ribosomal protein L10.位于酵母第十一染色体左臂上一个9.3 kb片段的序列揭示了五个开放阅读框，包括CCE1基因以及与MYO2和核糖体蛋白L10相关的推定产物。
Yeast. 1992 Nov;8(11):987-95. doi: 10.1002/yea.320081109.
5
Sequence analysis of a 3.5 Kb EcoRI fragment from the left arm of Saccharomyces cerevisiae chromosome XI reveals the location of the MBR1 gene and a sequence related to a GTPase-activating protein.对酿酒酵母第十一染色体左臂上一个3.5千碱基对的EcoRI片段进行序列分析，揭示了MBR1基因的位置以及一个与GTP酶激活蛋白相关的序列。
Yeast. 1994 Feb;10(2):257-64. doi: 10.1002/yea.320100212.
6
The sequence of a 17.5 kb DNA fragment on the left arm of yeast chromosome XI identifies the protein kinase gene ELM1, the DNA primase gene PRI2, a new gene encoding a putative histone and seven new open reading frames.酵母第十一染色体左臂上一个17.5 kb DNA片段的序列鉴定出蛋白激酶基因ELM1、DNA引发酶基因PRI2、一个编码假定组蛋白的新基因以及七个新的开放阅读框。
Yeast. 1993 Dec;9(12):1379-84. doi: 10.1002/yea.320091212.
7
Sequencing and analysis of a 20.5 kb DNA segment located on the left arm of yeast chromosome XI.对位于酵母第十一染色体左臂上的一段20.5千碱基对DNA片段进行测序和分析。
Yeast. 1994 Apr;10 Suppl A:S25-33. doi: 10.1002/yea.320100004.
8
Analysis of a 17.9 kb region from Saccharomyces cerevisiae chromosome VII reveals the presence of eight open reading frames, including BRF1 (TFIIIB70) and GCN5 genes.对酿酒酵母七号染色体上一个17.9 kb区域的分析表明，存在八个开放阅读框，包括BRF1（TFIIIB70）和GCN5基因。
Yeast. 1997 Mar 30;13(4):373-7. doi: 10.1002/(SICI)1097-0061(19970330)13:4<373::AID-YEA82>3.0.CO;2-V.
9
Sequence of a 7.8 kb segment on the left arm of yeast chromosome XI reveals four open reading frames, including the CAP1 gene, an intron-containing gene and a gene encoding a homolog to the mammalian UOG-1 gene.
Yeast. 1993 Mar;9(3):279-87. doi: 10.1002/yea.320090307.
10
The sequence of a 8 kb segment on the right arm of yeast chromosome VII identifies four new open reading frames and the genes for yTAFII145.酵母染色体VII右臂上一个8千碱基片段的序列鉴定出四个新的开放阅读框以及yTAFII145的基因。
Yeast. 1997 Mar 30;13(4):365-8. doi: 10.1002/(SICI)1097-0061(19970330)13:4<365::AID-YEA78>3.0.CO;2-F.

引用本文的文献

1
Function and regulation of yeast hexose transporters.酵母己糖转运蛋白的功能与调控
Microbiol Mol Biol Rev. 1999 Sep;63(3):554-69. doi: 10.1128/MMBR.63.3.554-569.1999.
2
Amino acid substitutions in membrane-spanning domains of Hol1, a member of the major facilitator superfamily of transporters, confer nonselective cation uptake in Saccharomyces cerevisiae.转运蛋白主要易化子超家族成员Hol1的跨膜结构域中的氨基酸替换赋予酿酒酵母非选择性阳离子摄取能力。
J Bacteriol. 1996 Dec;178(24):7197-205. doi: 10.1128/jb.178.24.7197-7205.1996.
3
Rgt1p of Saccharomyces cerevisiae, a key regulator of glucose-induced genes, is both an activator and a repressor of transcription.
酿酒酵母的Rgt1p是葡萄糖诱导基因的关键调节因子，它既是转录激活因子又是转录抑制因子。
Mol Cell Biol. 1996 Nov;16(11):6419-26. doi: 10.1128/MCB.16.11.6419.
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Two different repressors collaborate to restrict expression of the yeast glucose transporter genes HXT2 and HXT4 to low levels of glucose.两种不同的阻遏物协同作用，将酵母葡萄糖转运蛋白基因HXT2和HXT4的表达限制在低葡萄糖水平。
Mol Cell Biol. 1996 Oct;16(10):5536-45. doi: 10.1128/MCB.16.10.5536.