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慢性疲劳综合征的单纤维肌电图研究:重新评估

Single fibre EMG studies in chronic fatigue syndrome: a reappraisal.

作者信息

Roberts L, Byrne E

机构信息

Department of Neurology, St Vincent's Hospital, Fitzroy, Melbourne, Australia.

出版信息

J Neurol Neurosurg Psychiatry. 1994 Mar;57(3):375-6. doi: 10.1136/jnnp.57.3.375.

Abstract

Single fibre EMG studies were carried out on the right extensor digitorum communis muscle in 30 subjects with chronic fatigue syndrome and in 30 age and sex matched controls. Abnormal jitter was seen in five patients with chronic fatigue syndrome. Slight but significant differences between the mean consecutive differences in the remainder of the chronic fatigue subjects and the control subjects were recorded. Overall the differences were so minor that it seems unlikely that a disturbance of neuromuscular function as reflected by jitter measurement has a pathogenetic role. It is suggested that the increased jitter seen may be explained by the effects of the variability of motor unit firing rates on the myogenic component of the jitter.

摘要

对30例慢性疲劳综合征患者及30例年龄和性别相匹配的对照者的右指总伸肌进行了单纤维肌电图研究。在5例慢性疲劳综合征患者中观察到异常颤抖。记录了慢性疲劳受试者其余部分与对照受试者的平均连续差异之间存在轻微但显著的差异。总体而言,这些差异非常微小,以至于通过颤抖测量所反映的神经肌肉功能障碍似乎不太可能具有致病作用。有人认为,所观察到的颤抖增加可能是由运动单位放电频率的变异性对颤抖的肌源性成分的影响所解释的。

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