结核分枝杆菌脂质——索状因子的佐剂效应
Adjuvant effect of cord factor, a mycobacterial lipid.
作者信息
Saito R, Tanaka A, Sugiyama K, Azuma I, Yamamura Y
出版信息
Infect Immun. 1976 Mar;13(3):776-81. doi: 10.1128/iai.13.3.776-781.1976.
Abstract
Cord factor was a good adjuvant in mice and rats but exerted little if any adjuvant effect in guinea pigs. In rats, cord factor not only enhanced antibody production but also induced delayed hypersensitivity. Wax D was a weak adjuvant in mice. Cord factor caused a marked inflammatory swelling at the sites of injection in mice, but it caused no such swelling in rats and guinea pigs.
摘要
索状因子在小鼠和大鼠中是一种良好的佐剂，但在豚鼠中几乎没有佐剂效应。在大鼠中，索状因子不仅增强抗体产生，还诱导迟发型超敏反应。蜡质D在小鼠中是一种弱佐剂。索状因子在小鼠注射部位引起明显的炎性肿胀，但在大鼠和豚鼠中未引起这种肿胀。
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Adjuvant effect of cord factor, a mycobacterial lipid.结核分枝杆菌脂质——索状因子的佐剂效应
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