Tanaka A, Saito R, Sugiyama K, Morisaki I, Kotani S
Infect Immun. 1977 Jan;15(1):332-4. doi: 10.1128/iai.15.1.332-334.1977.
The minimal adjuvant-active structure in bacterial cell wall peptidoglycan for the induction of delayed hypersensitivity in rats (WKA) was the N-acetylmuramyl dipeptides (N-acetylmuramyl L-alanyl-D-isoglutamine and N-acetylmuramyl L-alanyl-D-glutamic acid).
在大鼠(WKA)中诱导迟发型超敏反应的细菌细胞壁肽聚糖中的最小佐剂活性结构是N-乙酰胞壁酰二肽(N-乙酰胞壁酰-L-丙氨酰-D-异谷氨酰胺和N-乙酰胞壁酰-L-丙氨酰-D-谷氨酸)。