Juárez-Figueroa L A, Hernández-Avila M, Uribe-Zúñiga P, Smulian G
Instituto Nacional de Salud Pública, México, Cuernavaca, Mor.
Rev Invest Clin. 1993 May-Jun;45(3):229-31.
P. carinii pneumonia affects more than 80% of patients with AIDS in developed countries. In Mexico this complication has been described in 12 to 23% of patients with AIDS, and it has been proposed that competitive disease such as TB and the low life expectancy of AIDS patients in Mexico are the possible explanations of this low percentage. However, in Mexico the frequency with which the population at risk of contracting AIDS is exposed to P. carinii is unknown. Therefore, we looked for P. carinii antibodies in a group of blood samples obtained in an AIDS detection center in Mexico City. A Western blot analysis was performed on 157 blood samples from homosexual and bisexual men and on 21 from female partners of HIV positive men. Positive results were obtained for 76.9% of the samples. No difference was observed in the frequency of P. carinii antibodies between HIV positive and negative individuals. Also, no differences by sex or age were found. Prevalence of P. carinii antibodies in this group is 76.9%, similar to that found in a comparable group in the U.S.
在发达国家，卡氏肺孢子虫肺炎影响超过80%的艾滋病患者。在墨西哥，12%至23%的艾滋病患者出现过这种并发症，有人提出，诸如结核病等竞争性疾病以及墨西哥艾滋病患者较低的预期寿命可能是这一低比例的原因。然而，在墨西哥，感染艾滋病风险人群接触卡氏肺孢子虫的频率尚不清楚。因此，我们在墨西哥城一个艾滋病检测中心采集的一组血样中寻找卡氏肺孢子虫抗体。对157份来自男同性恋者和双性恋男性的血样以及21份来自HIV阳性男性女性伴侣的血样进行了蛋白质印迹分析。76.9%的样本获得了阳性结果。在HIV阳性和阴性个体之间，卡氏肺孢子虫抗体的频率没有差异。此外，未发现性别或年龄方面的差异。该组中卡氏肺孢子虫抗体的患病率为76.9%，与美国一个可比组的患病率相似。
