Mao Q, Cao D, Jia X S
Guizhou Institute of Traditional Chinese Medicine, Guiyang.
Yao Xue Xue Bao. 1993;28(4):273-81.
Three bisdesmosidic triterpenoid saponins I-III, have been isolated from the flowers of Lonicera macranthoides Hand. -Mazz. By spectral (IR, MS, 1H-NMR and 13C-NMR) and chemical methods, I was proved to be identical with the known dipsacoside B, II and III were new compounds named macranthoidin A and macranthoidin B. Their structures were identified as follows: The prosapogenin of II, macranthoside A(IIb), was elucidated as 3-O-beta-D-glucopyranosyl-(1-3)-alpha-L-rhamnopyranosyl-(1-2)-alpha-L- arabinopyranosyl 3 beta, 23-dihydroxyl-olean-12-en-28-olic acid, II was established as 3-O-beta-D-glucopyranosyl-(1-3)-alpha-L-rhamnopyranosyl-(1-2)-alpha-L- arabinopyranosyl 3 beta,23-dihydroxyl-olean-12-en-28-O-beta-D-glucopyranosyl-(1-6)-beta-D- glucopyranoside. The prosapogenin of III, macranthoside B(IIIb), was elucidated as 3-O-beta-D-glucopyranosyl-(1-4)-beta-D-glucopyranosyl-(1-3)-alpha-L- rhamnopyranosyl-(1-2)-alpha-L-arabinopyranosyl 3 beta,23-dihydroxyl-olean-12-en-28-olic acid, III was established as 3-O-beta-D-glucopyranosyl-(1-4)-beta-D-glucopyranosyl-(1-3)-alpha-L- rhamnopyranosyl-(1-2)-alpha-L-arabinopyranosyl 3 beta,23-dihydroxyl-olean-12-en-28-O-beta-D-glucopyranosyl-(1-6)-beta-D- glucopyranoside. IIb and IIIb have not been reported in the literature.
从大花忍冬（Lonicera macranthoides Hand.-Mazz.）的花中分离出了三种双糖链三萜皂苷I - III。通过光谱法（红外光谱、质谱、1H核磁共振和13C核磁共振）和化学方法，证明I与已知的川续断皂苷B相同，II和III是新化合物，分别命名为大花忍冬苷A和大花忍冬苷B。它们的结构鉴定如下：II的前皂苷元大花忍冬苷A（IIb）被鉴定为3 - O - β - D - 吡喃葡萄糖基 -（1→3）- α - L - 吡喃鼠李糖基 -（1→2）- α - L - 阿拉伯吡喃糖基3β，23 - 二羟基 - 齐墩果 - 12 - 烯 - 28 - 酸，II被确定为3 - O - β - D - 吡喃葡萄糖基 -（1→3）- α - L - 吡喃鼠李糖基 -（1→2）- α - L - 阿拉伯吡喃糖基3β，23 - 二羟基 - 齐墩果 - 12 - 烯 - 28 - O - β - D - 吡喃葡萄糖基 -（1→6）- β - D - 吡喃葡萄糖苷。III的前皂苷元大花忍冬苷B（IIIb）被鉴定为3 - O - β - D - 吡喃葡萄糖基 -（1→4）- β - D - 吡喃葡萄糖基 -（1→3）- α - L - 吡喃鼠李糖基 -（1→2）- α - L - 阿拉伯吡喃糖基3β，23 - 二羟基 - 齐墩果 - 12 - 烯 - 28 - 酸，III被确定为3 - O - β - D - 吡喃葡萄糖基 -（1→4）- β - D - 吡喃葡萄糖基 -（1→3）- α - L - 吡喃鼠李糖基 -（1→2）- α - L - 阿拉伯吡喃糖基3β，23 - 二羟基 - 齐墩果 - 12 - 烯 - 28 - O - β - D - 吡喃葡萄糖基 -（1→6）- β - D - 吡喃葡萄糖苷。IIb和IIIb在文献中尚未见报道。
