Kitagawa I, Hori K, Uchida E, Chen W Z, Yoshikawa M, Ren J
Faculty of Pharmaceutical Sciences, Osaka University, P. R. China.
Chem Pharm Bull (Tokyo). 1993 Sep;41(9):1567-72. doi: 10.1248/cpb.41.1567.
From the air-dried roots of Glycyrrhiza uralensis Fischer collected in Xinjiang province, China ("Shinkyo-Kanzo" in Japanese), a new oleanene-type triterpene oligoglycoside named licorice-saponin L3 and a new chalcone oligoglycoside named isoliquiritin apioside were isolated together with glycyrrhizin, 18 alpha-glycyrrhizin, apioglycyrrhizin, araboglycyrrhizin, licorice-saponins A3, E2, G2, and H2, and six known flavonoid glycosides. On the basis of chemical and physicochemical evidence, the structures of licorice-saponin L3 and isoliquiritin apioside were elucidated as 3 beta-[alpha-L-rhamnopyranosyl(1-->2)-alpha-L-arabinopyranosyl(1--> 2)-beta-D-glucuronopyranosyloxy]-22 beta-acetoxy-24-hydroxyolean-12-en-30-oic acid (1) and 4-O-[beta-D-apiofuranosyl(1-->2)-beta-D- glucopyranosyl]isoliquiritigenin (6), respectively.
从采自中国新疆地区的甘草（日语称“Shinkyo-Kanzo”）的风干根中，分离得到了一种新的齐墩果烷型三萜寡糖苷，命名为甘草皂苷L3，以及一种新的查尔酮寡糖苷，命名为异甘草苷芹菜糖苷，同时还得到了甘草酸、18α-甘草酸、芹糖甘草酸、阿拉伯糖甘草酸、甘草皂苷A3、E2、G2和H2，以及六种已知的黄酮苷。基于化学和物理化学证据，甘草皂苷L3和异甘草苷芹菜糖苷的结构分别被确认为3β-[α-L-鼠李吡喃糖基(1→2)-α-L-阿拉伯吡喃糖基(1→2)-β-D-葡萄糖醛酸吡喃糖氧基]-22β-乙酰氧基-24-羟基齐墩果-12-烯-30-酸（1）和4-O-[β-D-芹菜呋喃糖基(1→2)-β-D-葡萄糖吡喃糖基]异甘草素（6）。
