van der Velden U, Abbas F, Armand S, de Graaff J, Timmerman M F, van der Weijden G A, van Winkelhoff A J, Winkel E G
Department of Oral Microbiology, Academic Centre for Dentistry, Amsterdam, The Netherlands.
J Clin Periodontol. 1993 Oct;20(9):683-90. doi: 10.1111/j.1600-051x.1993.tb00716.x.
The purpose of this investigation was to study clinically as well as microbiologically the effect of sibling relationship on the periodontal condition in a young population with a relatively high prevalence of periodontal disease and deprived from regular dental care. In this study, 23 family units consisting of 3 more siblings were evaluated. In all, 78 subjects aged 15 to 25 years were included in the study. The mean interproximal amount of loss of attachment in this population was 0.29 mm. The individual mean ranged from 0 to 1.27 mm. In 33% of the subjects, > or = 1 sites with a probing depth of 5 mm or more in conjunction with 2 mm of attachment loss were present. The results show a significant sibship effect for: plaque, calculus, loss of attachment, spirochetes on the tongue and in the pocket, Porphyromonas gingivalis on the gingiva and in the saliva and Prevotella intermedia in the saliva. These results support the hypothesis that periodontitis aggregates in families.
本研究的目的是从临床和微生物学角度，对牙周疾病患病率相对较高且缺乏定期牙科护理的年轻人群中，兄弟姐妹关系对牙周状况的影响进行研究。在本研究中，对由3个及以上兄弟姐妹组成的23个家庭单元进行了评估。该研究共纳入了78名年龄在15至25岁之间的受试者。该人群中附着丧失的平均邻间量为0.29毫米。个体平均值范围为0至1.27毫米。33%的受试者存在≥1个探诊深度为5毫米或更深且伴有2毫米附着丧失的位点。结果显示，在菌斑、牙石、附着丧失、舌部和龈袋中的螺旋体、牙龈和唾液中的牙龈卟啉单胞菌以及唾液中的中间普氏菌方面，存在显著的同胞关系效应。这些结果支持了牙周炎在家庭中聚集的假说。
