Lim L L, Valenti L A, Knapp J C, Dobson A J, Plotnikoff R, Higginbotham N, Heller R F
Centre for Clinical Epidemiology and Biostatistics, University of Newcastle, NSW, Australia.
J Clin Epidemiol. 1993 Nov;46(11):1249-56. doi: 10.1016/0895-4356(93)90089-j.
A slightly modified version of the Quality-of-Life after Myocardial Infarction (QLMI) questionnaire developed by Oldridge and colleagues was applied in a self-administered mode to patients with suspected acute myocardial infarction (AMI) in a randomized controlled trial of secondary prevention. Acceptability of the questionnaire was good, with 93% of responders answering all items. Factor analysis suggested three quality-of-life (QL) dimensions which we called "emotional", "physical" and "social". These differed somewhat from the dimensions proposed by Oldridge and colleagues. However, a sensitivity analysis showed relative invariance of results to weighting schemes. Scores on our three dimensions were responsive to differences between the treatment groups, and demonstrated construct validity based on associations between the measured QL and variables expected to affect QL. We conclude that the QLMI questionnaire has good potential as an instrument for assessing QL in post-AMI patients and that it can be successfully self-administered.
在一项二级预防随机对照试验中，采用了由奥尔德里奇及其同事编制的心肌梗死后生活质量（QLMI）问卷的一个稍有修改的版本，以自填方式应用于疑似急性心肌梗死（AMI）患者。问卷的可接受性良好，93%的应答者回答了所有项目。因子分析提示了三个生活质量（QL）维度，我们称之为“情感”、“身体”和“社会”维度。这些维度与奥尔德里奇及其同事提出的维度略有不同。然而，敏感性分析表明结果对加权方案具有相对不变性。我们三个维度的得分对治疗组之间的差异有反应，并基于所测QL与预期影响QL的变量之间的关联证明了结构效度。我们得出结论，QLMI问卷作为评估AMI后患者QL的工具具有良好潜力，并且可以成功地进行自填。
