罗德岛普罗维登斯血培养分离出的肺炎链球菌中红霉素和克拉霉素耐药率高
High rate of erythromycin and clarithromycin resistance among Streptococcus pneumoniae isolates from blood cultures from Providence, R.I.
作者信息
Lonks J R, Medeiros A A
机构信息
Brown University, Providence, Rhode Island.
出版信息
Antimicrob Agents Chemother. 1993 Sep;37(9):1742-5. doi: 10.1128/AAC.37.9.1742.
Abstract
Four (5%) of 81 recent isolates of Streptococcus pneumoniae from the blood of adult patients but no isolates from pediatric patients (n = 51) were resistant (MIC, > or = 1 microgram/ml) to erythromycin. The MICs of clarithromycin were slightly lower than those of erythromycin, but there was complete cross-resistance. Routine testing and surveillance are needed to determine whether erythromycin resistance among S. pneumoniae isolates is increasing throughout the United States.
摘要
在近期从成年患者血液中分离出的81株肺炎链球菌中，有4株（5%）对红霉素耐药（MIC≥1微克/毫升），但儿科患者（n = 51）中分离出的菌株未出现耐药情况。克拉霉素的MIC略低于红霉素，但存在完全交叉耐药。需要进行常规检测和监测，以确定美国各地肺炎链球菌分离株对红霉素的耐药性是否正在增加。
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