Patch length of localized repair events: role of DNA polymerase I in mutY-dependent mismatch repair.
作者信息
Radicella J P, Clark E A, Chen S, Fox M S
机构信息
Department of Biology, Massachusetts Institute of Technology, Cambridge 02139.
出版信息
J Bacteriol. 1993 Dec;175(23):7732-6. doi: 10.1128/jb.175.23.7732-7736.1993.
Abstract
In vivo experiments with heteroduplex lambda genomes show that the MutY mismatch repair system of Escherichia coli defines an average repair tract that is shorter than 27 nucleotides and longer than 9 nucleotides and extends 3' from the corrected adenine. The phenotype of a mutant defective in DNA polymerase I shows that this enzyme plays a significant, though not an essential, role in the in vivo repair of apurinic sites generated by this system. Evidence is presented that in the absence of polymerase I the repair tracts are modestly longer than in the polA+ extending in the 5' direction from the corrected adenine, suggesting a role for another DNA polymerase.
摘要
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本文引用的文献
1
A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity.
Anal Biochem. 1983 Jul 1;132(1):6-13. doi: 10.1016/0003-2697(83)90418-9.
2
Method for determining whether a gene of Escherichia coli is essential: application to the polA gene.
J Bacteriol. 1984 May;158(2):636-43. doi: 10.1128/jb.158.2.636-643.1984.
3
Specific mismatch correction in bacteriophage lambda crosses by very short patch repair.
Mol Gen Genet. 1983;191(1):118-25. doi: 10.1007/BF00330898.
4
New Tn10 derivatives for transposon mutagenesis and for construction of lacZ operon fusions by transposition.
Gene. 1984 Dec;32(3):369-79. doi: 10.1016/0378-1119(84)90012-x.
5
Construction of biologically functional bacterial plasmids in vitro.
Proc Natl Acad Sci U S A. 1973 Nov;70(11):3240-4. doi: 10.1073/pnas.70.11.3240.
6
Role of DNA polymerase I and the rec system in excision-repair in Escherichia coli.
Proc Natl Acad Sci U S A. 1972 May;69(5):1156-60. doi: 10.1073/pnas.69.5.1156.
7
Marker discrimination in transformation and mutation of pneumococcus.
Proc Natl Acad Sci U S A. 1973 Dec;70(12):3541-5. doi: 10.1073/pnas.70.12.3541.
8
Localized conversion in Streptococcus pneumoniae recombination: heteroduplex preference.
Genetics. 1985 Aug;110(4):557-68. doi: 10.1093/genetics/110.4.557.
9
Heteroduplex deoxyribonucleic acid base mismatch repair in bacteria.
Microbiol Rev. 1986 Jun;50(2):133-65. doi: 10.1128/mr.50.2.133-165.1986.
10
Repair of single base-pair transversion mismatches of Escherichia coli in vitro: correction of certain A/G mismatches is independent of dam methylation and host mutHLS gene functions.
Genetics. 1988 Apr;118(4):593-600. doi: 10.1093/genetics/118.4.593.
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