耐青霉素淋病奈瑟菌菌株中不存在青霉素降解酶。
Absence of penicillin-degrading enzymes in penicillin-resistant strains of Neisseria gonorrhoeae.
作者信息
Beebe J L, Ligeti P, Wlodkowski T J
出版信息
Antimicrob Agents Chemother. 1976 Jul;10(1):179-81. doi: 10.1128/AAC.10.1.179.
Abstract
Penicillin-resistant and -susceptible strains of Neisseria gonorrhoeae were evaluated for the presence of enzymes capable of degrading penicillin by incubation of [(14)C]benzylpenicillin with resting-cell suspensions of N. gonorrhoeae followed by extraction and chromatography of the labeled antibiotic. No degradative activity was observed.
摘要
通过将[(14)C]苄青霉素与淋病奈瑟菌的静息细胞悬液一起孵育，然后对标记抗生素进行提取和色谱分析，评估了耐青霉素和对青霉素敏感的淋病奈瑟菌菌株中是否存在能够降解青霉素的酶。未观察到降解活性。
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