Ferguson D A, Li C, Patel N R, Mayberry W R, Chi D S, Thomas E
Department of Microbiology, James H. Quillen College of Medicine, East Tennessee State University, Johnson City.
J Clin Microbiol. 1993 Oct;31(10):2802-4. doi: 10.1128/jcm.31.10.2802-2804.1993.
Helicobacter pylori was grown in low numbers from the saliva of one of nine patients who were positive for gastric H. pylori. The saliva-derived isolate from this patient was identical to the antral biopsy-derived isolate from the same patient and differed from isolates cultured from the antral biopsies of all other patients by soluble-protein electrophoresis, restriction endonuclease DNA analysis, and Southern blot hybridization. This is the first observation, to our knowledge, of the recovery of viable H. pylori from saliva.
在9例胃幽门螺杆菌阳性患者中,有1例患者的唾液中培养出少量幽门螺杆菌。该患者唾液分离株与同一患者胃窦活检分离株相同,且通过可溶性蛋白电泳、限制性内切酶DNA分析和Southern印迹杂交,与其他所有患者胃窦活检培养出的分离株不同。据我们所知,这是首次从唾液中分离出活的幽门螺杆菌。