Kishimoto R A, Veltri B J, Canonico P G, Shirey F G, Walker J S
Infect Immun. 1976 Oct;14(4):1087-96. doi: 10.1128/iai.14.4.1087-1096.1976.
An electron microscopic study was conducted to explore the interaction between normal guinea pig peritoneal macrophages and phase I and II Coxeilla burnetii previously treated with either normal or immune serum. A comparison was made on the efficiency of phagocytosis and subsequent killing of rickettsiae by macrophages. Both phases of rickettsiae previously treated with normal serum multiplied within phagosomes after phagocytosis with resultant destruction of macrophages. In contrast, suspending rickettsiae in immune serum rendered them more susceptible to phagocytosis and potentiated their destruction within macrophages.
进行了一项电子显微镜研究，以探讨正常豚鼠腹膜巨噬细胞与先前用正常血清或免疫血清处理过的I期和II期伯纳特柯克斯体之间的相互作用。对巨噬细胞吞噬立克次氏体并随后将其杀死的效率进行了比较。先前用正常血清处理过的两个阶段的立克次氏体在被吞噬后在吞噬体内繁殖，导致巨噬细胞被破坏。相比之下，将立克次氏体悬浮在免疫血清中使其更易被吞噬，并增强了它们在巨噬细胞内的破坏。
