Doignon F, Biteau N, Aigle M, Crouzet M
Laboratoire de Biologie Moléculaire et de Séquençage, Université de Bordeaux II, France.
Yeast. 1993 Oct;9(10):1131-7. doi: 10.1002/yea.320091014.
The DNA sequence of a 6794 bp fragment located at about 100 kb from the right telomere of chromosome II from Saccharomyces cerevisiae has been determined. Sequence analysis reveals five open reading frames. One is the ARO4 gene encoding the 3-deoxy-D-arabinoheptulosonate 7-phosphate synthase. Another presents strong homology with the S5 ribosomal protein from bacteria. The open reading frame YBR1705 shows significant homology with dUTPase, suggesting for the first time the existence of such an enzyme in S. cerevisiae.
已测定了位于酿酒酵母二号染色体右端粒约100 kb处的一段6794 bp片段的DNA序列。序列分析揭示了五个开放阅读框。一个是编码3-脱氧-D-阿拉伯庚酮糖酸7-磷酸合酶的ARO4基因。另一个与细菌的S5核糖体蛋白具有很强的同源性。开放阅读框YBR1705与dUTPase显示出显著的同源性,首次表明酿酒酵母中存在这种酶。