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通过使用药物提高正常人的记忆力。

Increase in the power of human memory in normal man through the use of drugs.

作者信息

Dimond S J, Brouwers E M

出版信息

Psychopharmacology (Berl). 1976 Sep 29;49(3):307-9. doi: 10.1007/BF00426834.

DOI:10.1007/BF00426834
PMID:826948
Abstract

Nootropyl (Piracetam) a drug reported to facilitate learning in animals was tested for its effect on man by administering it to normal volunteers. The subjects were given 3x4 capsules at 400 mg per day, in a double blind study. Each subject learned series of words presented as stimuli upon a memory drum. No effects were observed after 7 days but after 14 days verbal learning had significantly increased.

摘要

脑复康(吡拉西坦)是一种据报道能促进动物学习的药物,通过将其给予正常志愿者来测试其对人类的影响。在一项双盲研究中,受试者每天服用3次,每次4粒,每粒400毫克。每个受试者学习呈现在记忆鼓上作为刺激的一系列单词。7天后未观察到效果,但14天后言语学习显著增加。

相似文献

1
Increase in the power of human memory in normal man through the use of drugs.通过使用药物提高正常人的记忆力。
Psychopharmacology (Berl). 1976 Sep 29;49(3):307-9. doi: 10.1007/BF00426834.
2
[The effect of piracetam and nicergoline on conditioned-reflex memory under conditions of extreme exposure].
Farmakol Toksikol. 1990 May-Jun;53(3):8-10.
3
Effects of pyrithioxine, centrophenoxine, and piracetam on verbal learning.脑复新、氯酯醒和吡拉西坦对言语学习的影响。
Act Nerv Super (Praha). 1978 Dec;20(4):260-1.
4
Effects of oxiracetam on learning and memory in animals: comparison with piracetam.奥拉西坦对动物学习和记忆的影响:与吡拉西坦比较。
Clin Neuropharmacol. 1986;9 Suppl 3:S27-38.
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Comparative studies on the effects of the nootropic drugs adafenoxate, meclofenoxate and piracetam, and of citicholine on scopolamine-impaired memory, exploratory behavior and physical capabilities (experiments on rats and mice).关于促智药阿屈非尼、氯酯醒和吡拉西坦以及胞磷胆碱对东莨菪碱损害的记忆、探究行为和身体能力影响的比较研究(大鼠和小鼠实验)
Acta Physiol Pharmacol Bulg. 1988;14(1):3-13.
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Does piracetam counteract the ECT-induced memory dysfunctions in depressed patients?吡拉西坦能否对抗电休克治疗引起的抑郁症患者记忆功能障碍?
Acta Psychiatr Scand. 1975 Jun;51(5):319-26. doi: 10.1111/j.1600-0447.1975.tb00011.x.
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[Comparative study of the effect of picamilone and piracetam on learning in rats in a radial maze].匹卡米隆与吡拉西坦对大鼠放射状迷宫学习影响的比较研究
Farmakol Toksikol. 1989 Jul-Aug;52(4):14-7.
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Habituation of exploratory activity in mice: effects of combinations of piracetam and choline on memory processes.小鼠探索活动的习惯化:吡拉西坦与胆碱联合使用对记忆过程的影响。
Pharmacol Biochem Behav. 1984 Aug;21(2):209-12. doi: 10.1016/0091-3057(84)90216-8.
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Effect of piracetam on verbal memory of dyslexic boys.
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Failure of piracetam to facilitate acquisition or retention in younger or older rats.吡拉西坦未能促进幼龄或老龄大鼠的学习或记忆。
Exp Aging Res. 1980 Apr;6(2):175-80. doi: 10.1080/03610738008258354.

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J Clin Med. 2022 Jun 9;11(12):3310. doi: 10.3390/jcm11123310.
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Piracetam in developmental reading disorders: A review.吡拉西坦治疗发育性阅读障碍:综述
Eur Child Adolesc Psychiatry. 1994 Apr;3(2):59-71. doi: 10.1007/BF01977668.
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Piracetam for Aphasia in Post-stroke Patients: A Systematic Review and Meta-analysis of Randomized Controlled Trials.

本文引用的文献

1
Short-term retention of individual verbal items.单个言语项目的短期记忆
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Levodopa treatment of Parkinson's syndrome. Improved intellectual functioning.左旋多巴治疗帕金森综合征。改善智力功能。
吡拉西坦用于中风后失语症患者:随机对照试验的系统评价和荟萃分析
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A new chemotherapeutic investigation: Piracetam effects on dyslexia.一项新的化疗研究:吡拉西坦对诵读困难的影响。
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Piracetam in elderly psychiatric patients with mild diffuse cerebral impairment.吡拉西坦用于患有轻度弥漫性脑损伤的老年精神病患者。
Psychopharmacology (Berl). 1983;81(2):100-6. doi: 10.1007/BF00429000.
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'Cerebroactive' drugs. Clinical pharmacology and therapeutic role in cerebrovascular disorders.“脑活性”药物。临床药理学及在脑血管疾病中的治疗作用。
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High versus low-dose piracetam in alcohol organic mental disorder: a placebo controlled study.高剂量与低剂量吡拉西坦治疗酒精所致器质性精神障碍的对照研究:一项安慰剂对照试验
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4
The "nootropic" approach to the pharmacology of the integrative activity of the brain.关于大脑整合活动药理学的“促智”方法。
Cond Reflex. 1973 Apr-Jun;8(2):108-15. doi: 10.1007/BF03000311.
5
The clinical use of piracetam, a new nootropic drug. The treatment of symptoms of senile involution.新型益智药吡拉西坦的临床应用。老年衰退症状的治疗。
Arzneimittelforschung. 1972 Jun;22(6):975-7.