Vickers E R, Punnia-Moorthy A
Department of Oral Surgery, University of Sydney, Dental School, Australia.
Quintessence Int. 1993 Aug;24(8):547-51.
A new topical anesthetic agent, EMLA cream 5%, was investigated to determine if long application times could produce a degree of pulpal anesthesia. Thirteen subjects underwent testing in a double-blind manner. Pulpal anesthesia was assessed by electrical pulp testing. After the cream was applied for 15 to 30 minutes, 92% (12/13) of subjects reported no pain to the maximum setting of the pulp tester (300 V). The results of this study suggest EMLA cream has potential application in restorative dentistry and deserves further investigation.
一种新型局部麻醉剂——5%的复方利多卡因乳膏(EMLA乳膏),被用于研究长时间涂抹是否能产生一定程度的牙髓麻醉。13名受试者以双盲方式接受测试。通过牙髓电活力测试评估牙髓麻醉情况。在涂抹该乳膏15至30分钟后,92%(12/13)的受试者对牙髓测试仪的最大设置(300伏)未感到疼痛。该研究结果表明,EMLA乳膏在修复牙科中具有潜在应用价值,值得进一步研究。