Donaldson D, Meechan J G
Department of Oral Medical and Surgical Sciences, University of British Columbia, Vancouver, Canada.
Anesth Prog. 1995;42(1):7-10.
This investigation compared the use of a 5% eutectic mixture of local anesthetics (EMLA) cream to a "standard" intraoral topical anesthetic (5% lidocaine) as a means of anesthetizing the gingival sulcus in a double-blind, split-mouth study with human volunteers. A 5-min application of EMLA in a customized intraoral splint resulted in a significant increase in the depth of probing of the gingival sulcus without discomfort compared to a similar application of 5% lidocaine. Following application of EMLA, the pain-free probing depth measured at three sites in the upper premolar region increased by a mean total of 2.8 mm compared to an increase of 1.9 mm with lidocaine. This study suggests EMLA may be advantageous in providing periodontal anesthesia where manipulation of the gingiva is necessary.
在一项针对人类志愿者的双盲、双侧对照研究中，本调查比较了使用5%局部麻醉药共熔混合物（EMLA）乳膏与“标准”口腔内局部麻醉剂（5%利多卡因）麻醉牙龈沟的效果。与类似应用5%利多卡因相比，在定制的口腔内夹板中应用EMLA 5分钟，可显著增加牙龈沟探诊深度且无不适感。应用EMLA后，上前磨牙区三个部位无痛探诊深度平均总共增加2.8毫米，而利多卡因增加了1.9毫米。这项研究表明，在需要对牙龈进行操作时，EMLA在提供牙周麻醉方面可能具有优势。
