Shusterman D J
Division of Occupational and Environmental Medicine, University of California, San Francisco.
Occup Med. 1993 Jul-Sep;8(3):519-31.
Polymer fume fever usually occurs as a self-limited systemic illness with only minor pulmonary symptoms. Like metal fume fever, constitutional signs and symptoms typically present several hours after initial exposure, often giving rise to a misdiagnosis of viral "flu." Compared to metal fume fever, polymer fume fever has a more varied clinical presentation, the severity of which depends upon the specific conditions of exposure. When higher temperatures and/or longer durations of exposure are involved, significant pulmonary involvement, including radiographic consolidation, is a potential complication. Although a number of industrial outbreaks have implicated the smoking of contaminated cigarettes as a vehicle of exposure, any industrial or household activity in which PTFE is heated above 350-400 degrees C puts nearby workers or residents at risk of illness and is to be avoided without strict industrial hygiene controls.
聚合物烟雾热通常表现为一种自限性全身性疾病，仅有轻微肺部症状。与金属烟雾热一样，全身症状通常在初次接触数小时后出现，常导致误诊为病毒性“流感”。与金属烟雾热相比，聚合物烟雾热的临床表现更为多样，其严重程度取决于具体接触条件。当涉及更高温度和/或更长接触时间时，包括影像学实变在内的显著肺部受累是一种潜在并发症。尽管一些工业疫情表明吸食受污染香烟是一种接触途径，但任何将聚四氟乙烯加热至350 - 400摄氏度以上的工业或家庭活动都会使附近工人或居民面临患病风险，若无严格的工业卫生控制措施应避免此类活动。
