Hockley D J, Tripathi R C, Ashton N
Trans Ophthalmol Soc U K (1962). 1976 Jul;96(2):202-9.
Light and electron microscopical studies of monkey retinae after experimental branch vein occlusion by argon laser reveal that the immediate reaction in the corresponding region is one of capillary engorgement and dilatation followed by oedema (intra- and extracellular), and plasma leakage as shown by intravenous injection of horseradish peroxidase. Vascular stasis is characterized by packing of erythrocytes in the capillary lumen, early thrombus formation, and focal haemorrhages. Progressive degenerative changes in the endothelium and pericytes are seen in specimens taken a few hours to a few days after occlusion; within 3 to 4 weeks many vessels in the occluded region are reduced to basement membrane "ghosts" and the lumen and the cellular lodges of some vessels are subsequently invaded by proliferating glia, thus producing permanent capillary closure.
对实验性猴视网膜分支静脉阻塞后进行光镜和电镜研究发现，相应区域的即时反应是毛细血管充血和扩张，随后出现水肿（细胞内和细胞外），静脉注射辣根过氧化物酶显示有血浆渗漏。血管淤滞的特征是红细胞在毛细血管腔内堆积、早期血栓形成和局灶性出血。在阻塞后数小时至数天采集的标本中可见内皮细胞和周细胞的进行性退行性变化；在3至4周内，阻塞区域的许多血管缩小为基底膜“空壳”，随后一些血管的管腔和细胞腔被增殖的神经胶质细胞侵入，从而导致永久性毛细血管闭塞。
