Garcia N M, Del Negro G M, Heins-Vaccari E M, de Melo N T, de Assis C M, Lacaz C da S
Laboratório de Micologia Médica, Instituto de Medicina Tropical de São Paulo, Brasil.
Rev Inst Med Trop Sao Paulo. 1993 May-Jun;35(3):227-35. doi: 10.1590/s0036-46651993000300003.
The Authors show the results obtained through the study of a Paracoccidioides strain isolated from a penguin in the Uruguaian Antartide by GEZUELE et al. (1989). From the fecal mater it was isolated a fungus which was recently considered as a new species of the genus Paracoccidioides--P. antarcticus. However, the mycological and immunochemical studies including the demonstration of the 43 kDa glycoprotein by immunodiffusion test, SDS-PAGE and immunoelectrophoresis disclosed that such strain is similar to P. brasiliensis. Other studies, based on molecular taxonomy, including karyotyping, are the only tools to confirm the possibility of such strain to be a variant of P. brasiliensis. The Authors report the epidemiological significance of that finding and suggest a review in the knowledge of the ecological "niche" of P. brasiliensis.
作者展示了GEZUELE等人(1989年)通过对从乌拉圭南极地区一只企鹅身上分离出的副球孢子菌菌株进行研究而获得的结果。从粪便中分离出一种真菌,该真菌最近被认为是副球孢子菌属的一个新物种——南极副球孢子菌。然而,包括通过免疫扩散试验、SDS - PAGE和免疫电泳证明43 kDa糖蛋白在内的真菌学和免疫化学研究表明,该菌株与巴西副球孢子菌相似。基于分子分类学的其他研究,包括核型分析,是确认该菌株是否可能为巴西副球孢子菌变种的唯一工具。作者报告了这一发现的流行病学意义,并建议对巴西副球孢子菌生态“小生境”的认识进行重新审视。