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老年充血性心力衰竭患者再入院的预防:一项前瞻性随机试点研究的结果

Prevention of readmission in elderly patients with congestive heart failure: results of a prospective, randomized pilot study.

作者信息

Rich M W, Vinson J M, Sperry J C, Shah A S, Spinner L R, Chung M K, Davila-Roman V

机构信息

Geriatric Cardiology Section, Jewish Hospital at Washington University Medical Center, St. Louis, Missouri 63110.

出版信息

J Gen Intern Med. 1993 Nov;8(11):585-90. doi: 10.1007/BF02599709.

Abstract

OBJECTIVE

To determine the feasibility and potential impact of a non-pharmacologic multidisciplinary intervention for reducing hospital readmissions in elderly patients with congestive heart failure.

DESIGN

Prospective, randomized clinical trial, with 2:1 assignment to the study intervention or usual care.

SETTING

550-bed secondary and tertiary care university teaching hospital.

PATIENTS AND PARTICIPANTS

98 patients > or = 70 years of age (mean 79 +/- 6 years) admitted with documented congestive heart failure.

INTERVENTIONS

Comprehensive multidisciplinary treatment strategy consisting of intensive teaching by a geriatric cardiac nurse, a detailed review of medications by a geriatric cardiologist with specific recommendations designed to improve medication compliance and reduce side effects, early consultation with social services to facilitate discharge planning, dietary teaching by a hospital dietician, and close follow-up after discharge by home care and the study team.

MEASUREMENTS AND MAIN RESULTS

All patients were followed for 90 days after initial hospital discharge. The primary study endpoints were rehospitalization within the 90-day interval and the cumulative number of days hospitalized during follow-up. The 90-day readmission rate was 33.3% (21.7%-44.9%) for the patients receiving the study intervention (n = 63) compared with 45.7% (29.2%-62.2%) for the control patients (n = 35). The mean number of days hospitalized was 4.3 +/- 1.1 (2.1-6.5) for the treated patients vs 5.7 +/- 2.0 (1.8-9.6) for the usual-care patients. In a prospectively defined subgroup of patients at intermediate risk for readmission (n = 61), readmissions were reduced by 42.2% (from 47.6% to 27.5%; p = 0.10), and the average number of hospital days during follow-up decreased from 6.7 +/- 3.2 days to 3.2 +/- 1.2 days (p = NS).

CONCLUSIONS

These pilot data suggest that a comprehensive, multidisciplinary approach to reducing repetitive hospitalizations in elderly patients with congestive heart failure may lead to a reduction in readmissions and hospital days, particularly in patients at moderate risk for early rehospitalization. Further evaluation of this treatment strategy, including an assessment of the cost-effectiveness, is warranted.

摘要

目的

确定一种非药物多学科干预措施对降低老年充血性心力衰竭患者再入院率的可行性和潜在影响。

设计

前瞻性随机临床试验,按2:1分配至研究干预组或常规治疗组。

地点

拥有550张床位的二级和三级护理大学教学医院。

患者和参与者

98例年龄≥70岁(平均79±6岁)且确诊为充血性心力衰竭的患者。

干预措施

综合多学科治疗策略,包括老年心脏护士进行强化教学、老年心脏病专家详细审查药物并给出旨在提高用药依从性和减少副作用的具体建议、尽早咨询社会服务部门以促进出院计划安排、医院营养师进行饮食教学,以及出院后由家庭护理和研究团队进行密切随访。

测量指标和主要结果

所有患者在首次出院后随访90天。主要研究终点为90天内再次住院以及随访期间累计住院天数。接受研究干预的患者(n = 63)90天再入院率为33.3%(21.7%-44.9%),而对照组患者(n = 35)为45.7%(29.2%-62.2%)。治疗组患者平均住院天数为4.3±1.1(2.1-6.5)天,常规治疗组患者为5.7±2.0(1.8-9.6)天。在一个预先定义的再入院中度风险亚组患者(n = 61)中,再入院率降低了42.2%(从47.6%降至27.5%;p = 0.10),随访期间平均住院天数从6.7±3.2天降至3.2±1.2天(p = 无统计学意义)。

结论

这些初步数据表明,采用综合多学科方法减少老年充血性心力衰竭患者的重复住院,可能会降低再入院率和住院天数,尤其是在早期再入院中度风险患者中。有必要对这种治疗策略进行进一步评估,包括成本效益评估。

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