Young R C
Fox Chase Cancer Center, Philadelphia, Pa.
Arch Otolaryngol Head Neck Surg. 1993 Jul;119(7):732-4. doi: 10.1001/archotol.1993.01880190028005.
Increasing attention is being paid to cancer prevention as the best and most cost-effective way to address the cancer problem. Efforts have focused on the modification of high-risk behavior as well as the development of chemoprevention agents that may reduce or modify the development of cancer. In each of the areas of cancer prevention research, specific studies and trials have been and are being performed in oropharyngeal cancers. These include extensive programs of behavior modification such as smoking cessation and studies of synthetic retinoids and other chemopreventative agents in head and neck cancers, esophageal cancer, and other oropharyngeal cancers. One of the problems that compromises this effort is the distorted public perception of risk where rare risk factors are often given more emphasis than the more important dangers such as alcohol and tobacco use.
作为应对癌症问题的最佳且最具成本效益的方式，癌症预防正受到越来越多的关注。相关努力聚焦于改变高危行为以及研发可能减少或改变癌症发生的化学预防剂。在癌症预防研究的各个领域，针对口咽癌已经开展并正在进行具体的研究和试验。这些包括广泛的行为改变项目，如戒烟，以及对头颈部癌、食管癌和其他口咽癌中合成维甲酸及其他化学预防剂的研究。影响这项工作的一个问题是公众对风险的认知扭曲，即罕见的风险因素往往比酒精和烟草使用等更重要的危险因素受到更多强调。
