Childs C
University of Manchester, North Western Injury Research Centre.
Arch Dis Child. 1993 May;68(5):658-61. doi: 10.1136/adc.68.5.658.
This study characterised the pattern of oxygen consumption (VO2) in healthy infants and children asleep and awake (at rest) in a thermoneutral environment. Measurement of respiratory gas exchange (VO2 and VCO2) was made using an open circuit flow through system of indirect calorimetry with a specially designed facemask for the collection of exhaled breath. Fifty two healthy subjects aged 4.5 months to 12.8 years were studied for 15-20 minutes; 18 during sleep and 34 at rest (awake). There was a curvilinear relation between VO2 and age in the two groups and children aged 2 years or less had the highest values. The value of VO2 was significantly higher in the awake subjects (12.5-15.0 ml/min/kg compared with 7.5-9.0 ml/min/kg in sleeping children). Comparison of the regression lines after log transformation of these data showed a significant difference in VO2 of resting and sleeping subjects up to the age of 9.5 years.
本研究描绘了健康婴幼儿在热中性环境中睡眠和清醒（静息状态）时的耗氧量（VO₂）模式。采用开放式流通系统的间接测热法，通过一个专门设计的用于收集呼出气体的面罩来测量呼吸气体交换（VO₂和VCO₂）。对52名年龄在4.5个月至12.8岁的健康受试者进行了15 - 20分钟的研究；其中18名在睡眠状态，34名处于静息（清醒）状态。两组的VO₂与年龄之间均呈曲线关系，2岁及以下儿童的VO₂值最高。清醒受试者的VO₂值显著更高（12.5 - 15.0毫升/分钟/千克，而睡眠儿童为7.5 - 9.0毫升/分钟/千克）。对这些数据进行对数转换后，比较回归线发现，9.5岁以下静息和睡眠受试者的VO₂存在显著差异。
