Jenney M E, Childs C, Mabin D, Beswick M V, David T J
Department of Child Health, University of Manchester, Booth Hall Children's Hospital.
Arch Dis Child. 1995 Feb;72(2):144-6. doi: 10.1136/adc.72.2.144.
Measurements of oxygen consumption (VO2) were made during sleep in 10 patients with atopic dermatitis. Two groups of healthy children acted as controls. All subjects were studied in bed in an environmental temperature of 24-26 degrees C, and sleep was confirmed during continuous electroencephalographic monitoring. Mean (SD) values of VO2 in sleeping patients who were not scratching ranged from 4.0 (0.4) to 7.4 (0.7), which was not statistically significantly different from control values which ranged from 3.24 (0.3) to 5.56 (0.4). During scratching (while asleep), which occurred in nine out of 10 patients with atopic dermatitis, the mean values of VO2 ranged from 4.5 (0.04) to 10.4 (2.7), and this was significantly higher than the non-scratching patients and the control values. Scratching during sleep in children with atopic dermatitis is associated with increased VO2.
对10例特应性皮炎患者在睡眠期间的耗氧量（VO2）进行了测量。两组健康儿童作为对照。所有受试者均在环境温度为24 - 26摄氏度的床上进行研究，并且在连续脑电图监测期间确认处于睡眠状态。未搔抓的睡眠患者的VO2均值（标准差）范围为4.0（0.4）至7.4（0.7），与对照值范围3.24（0.3）至5.56（0.4）相比，无统计学显著差异。在10例特应性皮炎患者中有9例在睡眠期间出现搔抓，此时VO2均值范围为4.5（0.04）至10.4（2.7），这显著高于未搔抓患者及对照值。特应性皮炎患儿睡眠期间的搔抓与VO2增加有关。
