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全科医疗中失眠症的患病率及治疗:一项纵向研究

Prevalence and treatment of insomnia in general practice. A longitudinal study.

作者信息

Hohagen F, Rink K, Käppler C, Schramm E, Riemann D, Weyerer S, Berger M

机构信息

Psychiatric Department, University of Freiburg, Germany.

出版信息

Eur Arch Psychiatry Clin Neurosci. 1993;242(6):329-36. doi: 10.1007/BF02190245.

Abstract

The aim of the study was to assess prevalence and treatment modalities of insomnia in general practice. To investigate the course of insomnia, a longitudinal study design was adopted. Two thousand five hundred and twelve patients (age 18-65 years) were investigated with a questionnaire in general practice (T1). Four months later (T2) and again 2 years later (T3) a questionnaire was sent to all patients who had complained about severe insomnia at the time of the first inquiry. To assess insomnia, operationalized diagnostic criteria were applied (DSM-III-R). Eighteen point seven percent suffered from severe, 12.2% suffered from moderate and 15% suffered from mild insomnia. In the course of 2 years insomnia appeared as a chronic health problem. A high comorbidity of severe insomnia was found with chronic somatic and psychiatric disorders, especially with depression. Of the severely insomniac patients, 23.9% used prescribed hypnotics habitually, mainly benzodiazepines. The use of prescribed hypnotics remained rather stable during the whole study period. More than half of the patients reported a daily use of the hypnotics for 1-5 years or longer, but only 22% of the severely insomniac patients reported at the time of the third inquiry a significant improvement of insomnia due to the administration of sleeping pills. Thus, the long-term administration of benzodiazepine hypnotics seems to be an inadequate treatment strategy in chronic insomnia. Whether the occurrence of rebound insomnia after benzodiazepine withdrawal may be one of the main factors for chronic hypnotic use requires discussion.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

本研究旨在评估全科医疗中失眠症的患病率及治疗方式。为调查失眠症的病程,采用了纵向研究设计。在全科医疗中,对2512名患者(年龄18 - 65岁)进行了问卷调查(T1)。四个月后(T2)以及两年后(T3),向所有在首次调查时抱怨有严重失眠症的患者再次发送问卷。为评估失眠症,应用了操作性诊断标准(DSM - III - R)。18.7%的患者患有严重失眠症,12.2%患有中度失眠症,15%患有轻度失眠症。在两年的病程中,失眠症表现为一种慢性健康问题。发现严重失眠症与慢性躯体和精神疾病,尤其是抑郁症,存在高度共病现象。在严重失眠症患者中,23.9%习惯性使用处方催眠药,主要是苯二氮䓬类药物。在整个研究期间,处方催眠药的使用情况保持相对稳定。超过一半的患者报告每日使用催眠药达1 - 5年或更长时间,但在第三次调查时,只有22%的严重失眠症患者报告因服用安眠药而失眠症有显著改善。因此,长期使用苯二氮䓬类催眠药似乎不是治疗慢性失眠症的合适策略。苯二氮䓬类药物撤药后出现的反弹性失眠是否可能是长期使用催眠药的主要因素之一,这需要探讨。(摘要截选至250词)

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