Urschel J D
Department of Surgery, Misericordia Hospital, Edmonton, Alberta, Canada.
Am J Surg. 1993 Jul;166(1):68-70. doi: 10.1016/s0002-9610(05)80587-2.
In order to determine the in-hospital morbidity and mortality rates of antireflux surgery in a community hospital setting, a retrospective 10-year review of 355 antireflux procedures was conducted. A modified Nissen fundoplication, with an incomplete fundal wrap, was the most common operation performed. Concomitant procedures, usually biliary or gastric, were undertaken in 93 patients. Thirty-nine patients had previously undergone an operation involving hiatal dissection. Overall morbidity was 17%, and mortality was 1% (three deaths). Patients with previous hiatal surgery had higher morbidity (44%, p < 0.0001) and mortality rates (3%, p < 0.21). Wound infection occurred in 5% of patients and wound dehiscence in 1%. Splenic repair or splenectomy for iatrogenic injury was required in 2%. Postoperative gastroesophageal leaks occurred in six patients (2%). Patients with previous hiatal surgery had a higher incidence of gastroesophageal leaks (8%, p < 0.002). Three of six patients had contained leaks that resolved with antibiotics, cessation of oral intake, and nutritional support. Two of three patients with noncontained leaks died despite surgical intervention.
为了确定社区医院环境下抗反流手术的院内发病率和死亡率,对355例抗反流手术进行了为期10年的回顾性研究。最常见的手术是改良的nissen胃底折叠术,胃底包裹不完全。93例患者进行了联合手术,通常是胆道或胃部手术。39例患者此前接受过涉及裂孔解剖的手术。总体发病率为17%,死亡率为1%(3例死亡)。既往接受过裂孔手术的患者发病率(44%,p<0.0001)和死亡率(3%,p<0.21)更高。5%的患者发生伤口感染,1%的患者发生伤口裂开。2%的患者因医源性损伤需要进行脾脏修复或脾切除术。6例患者(2%)发生术后胃食管漏。既往接受过裂孔手术的患者胃食管漏发生率更高(8%,p<0.002)。6例患者中有3例的漏出被控制,通过抗生素、停止经口摄入和营养支持得以解决。3例未被控制漏出的患者中有2例尽管接受了手术干预仍死亡。