胞壁酰肽。化学结构、生物活性及作用机制。 - Suppr

Suppr

超能文献

Muramyl peptides. Chemical structure, biological activity and mechanism of action.

作者信息

Adam A, Petit J F, Lefrancier P, Lederer E

出版信息

Mol Cell Biochem. 1981 Dec 4;41:27-47. doi: 10.1007/BF00225295.

DOI:10.1007/BF00225295

PMID:7035868

Abstract

摘要

相似文献

Muramyl peptides. Chemical structure, biological activity and mechanism of action.胞壁酰肽。化学结构、生物活性及作用机制。

Mol Cell Biochem. 1981 Dec 4;41:27-47. doi: 10.1007/BF00225295.

Fate of the synthetic immunoadjuvant, muramyl dipeptide (14C-labelled) in the mouse.合成免疫佐剂胞壁酰二肽（14C标记）在小鼠体内的命运

Int J Immunopharmacol. 1979;1(1):35-41. doi: 10.1016/0192-0561(79)90028-6.

Recent developments concerning muramyl dipeptide, a synthetic immunoregulating molecule.关于胞壁酰二肽（一种合成免疫调节分子）的最新进展。

J Reticuloendothel Soc. 1979 Dec;26(Suppl):631-41.

A novel muramyl peptide derivative stimulates tumoricidal activity of macrophages and antibody production by B cells.一种新型胞壁酰肽衍生物可刺激巨噬细胞的杀肿瘤活性及B细胞产生抗体。

FEBS Lett. 1987 Aug 10;220(1):93-7. doi: 10.1016/0014-5793(87)80882-7.

Role of muramyl peptides for the enhancement of synthetic vaccines.胞壁酰肽在增强合成疫苗方面的作用。

Dev Biol Stand. 1986;63:133-40.

Immunoadjuvant effects of the synthetic muramyl-dipeptide (MDP) N-acetylmuramyl-L-alanyl-D-isoglutamine.合成的胞壁酰二肽（MDP）N-乙酰胞壁酰-L-丙氨酰-D-异谷氨酰胺的免疫佐剂作用。

Z Immunitatsforsch Immunobiol. 1978 Oct;155(1):87-92.

An adjuvant formulation based on N-acetylglucosaminyl-N-acetylmuramyl-L-alanyl-D-isoglutamine with dimethyldioctadecylammonium chloride and zinc-L-proline complex as synergists.一种基于N-乙酰葡糖胺基-N-乙酰胞壁酰-L-丙氨酰-D-异谷氨酰胺，并以二甲基二辛基氯化铵和L-脯氨酸锌络合物作为增效剂的佐剂配方。

Immunol Lett. 1995 Jan;44(1):19-24. doi: 10.1016/0165-2478(94)00188-w.

Biological activity of a new synthetic muramyl peptide adjuvant devoid of pyrogenicity.一种无致热原性的新型合成胞壁酰肽佐剂的生物活性。

Infect Immun. 1982 Feb;35(2):417-24. doi: 10.1128/iai.35.2.417-424.1982.

Efficient genetically controlled formation of antibody to a synthetic antigen [poly(LTyr, LGlu)-poly(DLAla)- -poly(LLys)] covalently bound to a synthetic adjuvant (N-acetylmuramyl-L-alanyl-D-isoglutamine).高效地通过基因控制形成针对与合成佐剂（N-乙酰胞壁酰-L-丙氨酰-D-异谷氨酰胺）共价结合的合成抗原[聚（L-酪氨酸，L-谷氨酸）-聚（D-丙氨酸）-聚（L-赖氨酸）]的抗体。

Proc Natl Acad Sci U S A. 1980 Aug;77(8):4933-7. doi: 10.1073/pnas.77.8.4933.

Freund's adjuvant, NOD2 and mycobacteria.福氏完全佐剂、NOD2 和分枝杆菌。

Curr Opin Microbiol. 2015 Feb;23:126-32. doi: 10.1016/j.mib.2014.11.015. Epub 2014 Dec 5.

引用本文的文献

Immunogenic molecules associated with gut bacterial cell walls: chemical structures, immune-modulating functions, and mechanisms.与肠道细菌细胞壁相关的免疫原性分子：化学结构、免疫调节功能和机制。

Protein Cell. 2023 Oct 25;14(10):776-785. doi: 10.1093/procel/pwad016.

Strategies for Using Muramyl Peptides - Modulators of Innate Immunity of Bacterial Origin - in Medicine.利用细菌来源的天然免疫调节剂——菌壁酰肽的策略在医学中的应用。

Front Immunol. 2021 Apr 20;12:607178. doi: 10.3389/fimmu.2021.607178. eCollection 2021.

Recognition of Extracellular Bacteria by NLRs and Its Role in the Development of Adaptive Immunity.NLRs对胞外细菌的识别及其在适应性免疫发育中的作用

Front Immunol. 2013 Oct 21;4:344. doi: 10.3389/fimmu.2013.00344.

Muramyl dipeptide and its derivatives: peptide adjuvant in immunological disorders and cancer therapy.胞壁酰二肽及其衍生物：免疫紊乱和癌症治疗中的肽佐剂

Curr Bioact Compd. 2011 Sep;7(3):180-197. doi: 10.2174/157340711796817913.

Structure-activity relationships in nucleotide oligomerization domain 1 (Nod1) agonistic γ-glutamyldiaminopimelic acid derivatives.核苷酸寡聚化结构域 1（Nod1）激动剂 γ-谷氨酰二氨基庚二酸衍生物的构效关系。

J Med Chem. 2011 Mar 10;54(5):1490-510. doi: 10.1021/jm101535e. Epub 2011 Feb 7.

The ever-expanding function of NOD2: autophagy, viral recognition, and T cell activation.NOD2 不断扩展的功能：自噬、病毒识别和 T 细胞激活。

Trends Immunol. 2011 Feb;32(2):73-9. doi: 10.1016/j.it.2010.12.007. Epub 2011 Jan 19.

Modulation of adaptive immunity by different adjuvant-antigen combinations in mice lacking Nod2.在缺乏Nod2的小鼠中，不同佐剂-抗原组合对适应性免疫的调节作用

Vaccine. 2008 Oct 29;26(46):5808-13. doi: 10.1016/j.vaccine.2008.08.038. Epub 2008 Sep 27.

NLR proteins: integral members of innate immunity and mediators of inflammatory diseases.NLR蛋白：先天免疫的重要成员及炎症性疾病的介质

J Leukoc Biol. 2008 Jan;83(1):13-30. doi: 10.1189/jlb.0607402. Epub 2007 Sep 17.

Probiotic bacteria stimulate virus-specific neutralizing antibodies following a booster polio vaccination.在脊髓灰质炎疫苗加强接种后，益生菌可刺激产生病毒特异性中和抗体。

Eur J Nutr. 2005 Oct;44(7):406-13. doi: 10.1007/s00394-004-0541-8. Epub 2004 Dec 1.

Production of interleukin-12 by murine macrophages in response to bacterial peptidoglycan.鼠巨噬细胞对细菌肽聚糖产生白细胞介素-12。

Infect Immun. 1998 Oct;66(10):4947-9. doi: 10.1128/IAI.66.10.4947-4949.1998.

本文引用的文献

The influence of components of M. tuberculosis and other Mycobacteria upon antibody production to ovalbumin.结核分枝杆菌及其他分枝杆菌的成分对卵清蛋白抗体产生的影响。

Immunology. 1958 Jan;1(1):54-66.

The mode of action of immunologic adjuvants.免疫佐剂的作用方式。

Bibl Tuberc. 1956(10):130-48.

[Not Available].

FEBS Lett. 1969 Jul;4(2):87-92. doi: 10.1016/0014-5793(69)80203-6.

Effect of indomethacin on increased resistance to bacterial infection and on febrile responses induced by muramyl dipeptide.消炎痛对细菌感染抵抗力增强及对胞壁酰二肽诱导的发热反应的影响。

J Infect Dis. 1980 Nov;142(5):708-15. doi: 10.1093/infdis/142.5.708.

Synthesis of conjugates containing N-acetylmuramyl-L-alanyl-D-isoglutaminyl (MDP). Their use as hapten-carrier systems.含N-乙酰胞壁酰-L-丙氨酰-D-异谷氨酰胺（MDP）的缀合物的合成。它们作为半抗原-载体系统的用途。

Mol Immunol. 1980 Mar;17(3):357-63. doi: 10.1016/0161-5890(80)90056-5.

Dissociation of immunostimulant activities of muramyl dipeptide (MDP) by linking amino-acids or peptides to the glutaminyl residue.通过将氨基酸或肽连接到谷氨酰胺残基上来分离胞壁酰二肽（MDP）的免疫刺激活性。

Biochem Biophys Res Commun. 1980 Sep 30;96(2):915-23. doi: 10.1016/0006-291x(80)91442-4.

Central pyrogenic activity of muramyl dipeptide.胞壁酰二肽的中枢致热活性。

J Exp Med. 1980 Oct 1;152(4):869-77. doi: 10.1084/jem.152.4.869.

Muramyl dipeptide-induced adjuvant arthritis.胞壁酰二肽诱导的佐剂性关节炎

Infect Immun. 1980 May;28(2):624-6. doi: 10.1128/iai.28.2.624-626.1980.

Immunostimulant activities of a lipophilic muramyl dipeptide derivative and of desmuramyl peptidolipid analogs.一种亲脂性胞壁酰二肽衍生物和去胞壁酰肽脂类似物的免疫刺激活性。

Infect Immun. 1980 Mar;27(3):826-31. doi: 10.1128/iai.27.3.826-831.1980.

The metabolic fate of 14C-labeled peptidoglycan monomer in mice. I. Identification of the monomer and the corresponding pentapeptide in urine.14C标记的肽聚糖单体在小鼠体内的代谢命运。I. 尿液中单体及相应五肽的鉴定。

Biochim Biophys Acta. 1980 Apr 17;629(1):77-82. doi: 10.1016/0304-4165(80)90266-4.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验